[HTML][HTML] The human fatty acid-binding protein family: evolutionary divergences and functions
RL Smathers, DR Petersen - Human genomics, 2011 - Springer
Fatty acid-binding proteins (FABPs) are members of the intracellular lipid-binding protein
(iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and …
(iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and …
[HTML][HTML] Tissue-specific functions in the fatty acid-binding protein family
J Storch, AE Thumser - Journal of Biological Chemistry, 2010 - ASBMB
The intracellular fatty acid-binding proteins (FABPs) are abundantly expressed in almost all
tissues. They exhibit high affinity binding of a single long-chain fatty acid, with the exception …
tissues. They exhibit high affinity binding of a single long-chain fatty acid, with the exception …
The emerging functions and mechanisms of mammalian fatty acid–binding proteins
Fatty acid–binding proteins (FABPs) are abundant intracellular proteins that bind long-chain
fatty acids with high affinity. Nine separate mammalian FABPs have been identified, and …
fatty acids with high affinity. Nine separate mammalian FABPs have been identified, and …
[HTML][HTML] Structural and functional analysis of fatty acid-binding proteins
J Storch, L McDermott - Journal of lipid research, 2009 - ASBMB
The mammalian FA-binding proteins (FABPs) bind long-chain FA with high affinity. The large
number of FABP types is suggestive of distinct functions in specific tissues. Multiple …
number of FABP types is suggestive of distinct functions in specific tissues. Multiple …
Liver fatty acid-binding protein and obesity
BP Atshaves, GG Martin, HA Hostetler… - The Journal of nutritional …, 2010 - Elsevier
While low levels of unesterified long chain fatty acids (LCFAs) are normal metabolic
intermediates of dietary and endogenous fat, LCFAs are also potent regulators of key …
intermediates of dietary and endogenous fat, LCFAs are also potent regulators of key …
Gut-inhabiting Clostridia build human GPCR ligands by conjugating neurotransmitters with diet-and human-derived fatty acids
FY Chang, P Siuti, S Laurent, T Williams… - Nature …, 2021 - nature.com
Human physiology is regulated by endogenous signalling compounds, including fatty acid
amides (FAAs), chemical mimics of which are made by bacteria. The molecules produced by …
amides (FAAs), chemical mimics of which are made by bacteria. The molecules produced by …
U‐Shaped Conformation of Alkyl Chains Bound to a Synthetic Host
Long-chain fatty acids play important roles in cellular metabolism both as metabolic fuels
and also as building blocks for membrane-forming complex lipids. Fatty acid binding …
and also as building blocks for membrane-forming complex lipids. Fatty acid binding …
Fatty acid transporters involved in the palmitate and oleate induced insulin resistance in primary rat hepatocytes
A Chabowski, M Żendzian‐Piotrowska… - Acta …, 2013 - Wiley Online Library
Aims To determine the presence and possible involvement of FAT/CD 36, FABP pm and
FATP‐2, transporters in (i) fatty acids movement across plasma membrane and (ii) an …
FATP‐2, transporters in (i) fatty acids movement across plasma membrane and (ii) an …
Impact of intracellular lipid binding proteins on endogenous and xenobiotic ligand metabolism and disposition
KCB Yabut, N Isoherranen - Drug Metabolism and Disposition, 2023 - ASPET
The family of intracellular lipid binding proteins (iLBPs) is comprised of 16 members of
structurally related binding proteins that have ubiquitous tissue expression in humans. iLBPs …
structurally related binding proteins that have ubiquitous tissue expression in humans. iLBPs …
Interactions between human liver fatty acid binding protein and peroxisome proliferator activated receptor selective drugs
T Velkov - PPAR research, 2013 - Wiley Online Library
Fatty acid binding proteins (FABPs) act as intracellular shuttles for fatty acids as well as
lipophilic xenobiotics to the nucleus, where these ligands are released to a group of nuclear …
lipophilic xenobiotics to the nucleus, where these ligands are released to a group of nuclear …