Multi-omics profiling: the way toward precision medicine in metabolic diseases

C Hu, W Jia - Journal of molecular cell biology, 2021 - academic.oup.com
Metabolic diseases including type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver
disease (NAFLD), and metabolic syndrome (MetS) are alarming health burdens around the …

Flavonoids and insulin-resistance: from molecular evidences to clinical trials

B Russo, F Picconi, I Malandrucco… - International journal of …, 2019 - mdpi.com
Insulin-resistance is one of the main factors responsible for the onset and progression of
Metabolic Syndrome (MetS). Among all polyphenols, the effects of flavonoids and their main …

Multiomics technologies: role in disease biomarker discoveries and therapeutics

MA Dar, A Arafah, KA Bhat, A Khan… - Briefings in …, 2023 - academic.oup.com
Medical research has been revolutionized after the publication of the full human genome.
This was the major landmark that paved the way for understanding the biological functions …

Matrix metalloproteinase-9 (MMP-9) gene polymorphism in stroke patients

K Buraczynska, J Kurzepa, A Ksiazek… - Neuromolecular …, 2015 - Springer
Matrix metalloproteinases (MMPs), endopeptidases degrading extracellular matrix, play an
important role in the pathogenesis of atherosclerosis and vascular disease. The aim of this …

[HTML][HTML] Precision medicine and metabolic syndrome

M Gharipour, P Nezafati, L Sadeghian… - ARYA …, 2022 - ncbi.nlm.nih.gov
Metabolic syndrome (MetS) is one of the most important health issues around the world and
a major risk factor for both type 2 diabetes mellitus (T2DM) and cardiovascular diseases …

[HTML][HTML] Sex-specific differences in the association between APOE genotype and metabolic syndrome among middle-aged and older rural Indians

S Azhuvalappil, R Prasad, P Sahadevan, H Pradhan… - Metabolism Open, 2024 - Elsevier
Abstract Background Metabolic syndrome (MetS), characterized by elevated blood pressure,
high blood glucose, excess abdominal fat, and abnormal cholesterol or triglyceride levels …

Effect of Lactobacillus plantarum fermented barley on plasma glycolipids and insulin sensitivity in subjects with metabolic syndrome

R Pan, T Xu, J Bai, S Xia, Q Liu, J Li… - Journal of Food …, 2020 - Wiley Online Library
Fermented barley (FB) flour by Lactobacillus plantarum is richer in dietary fiber, polyphenols,
gamma‐aminobutyric acid, and other biologically active ingredients. This study aimed to …

A Genome-wide study of blood pressure in African Americans accounting for gene-smoking interaction

JY Taylor, K Schwander, SLR Kardia, D Arnett… - Scientific reports, 2016 - nature.com
Cigarette smoking has been shown to be a health hazard. In addition to being considered a
negative lifestyle behavior, studies have shown that cigarette smoking has been linked to …

Association of vitamin D receptor gene polymorphisms with serum 25 (OH) D levels and metabolic syndrome in Thai population

B Sangkaew, M Nuinoon, N Jeenduang - Gene, 2018 - Elsevier
Metabolic syndrome (MetS) increases the risk of developing cardiovascular disease (CVD)
and type 2 diabetes mellitus (T2DM). The vitamin D receptor gene (VDR) polymorphisms …

Improving‐omics‐based research and precision health in minority populations: Recommendations for nurse scientists

JY Taylor… - Journal of Nursing …, 2018 - Wiley Online Library
Purpose The purpose of this article is to provide an overview of the role of nurse scientists in‐
omics‐based research and to promote discussion around the conduct of‐omics‐based …