Developmental functions of the Distal-less/Dlx homeobox genes

G Panganiban, JLR Rubenstein - 2002 - journals.biologists.com
Distal-less is the earliest known gene specifically expressed in developing insect limbs; its
expression is maintained throughout limb development. The homeodomain transcription …

DLX Genes: Roles in Development and Cancer

Y Tan, JR Testa - Cancers, 2021 - mdpi.com
Simple Summary DLX homeobox family genes encode transcription factors that have
indispensable roles in embryonic and postnatal development. These genes are critically …

Robustness and evolvability in living systems

A Wagner - 2013 - torrossa.com
Living things are unimaginably complex, yet they have withstood a withering assault of
harmful influences over several billion years. These influences include cataclysmic changes …

Specification of Jaw Subdivisions by Dlx Genes

MJ Depew, T Lufkin, JLR Rubenstein - science, 2002 - science.org
The success of vertebrates was due in part to the acquisition and modification of jaws. Jaws
are principally derived from the branchial arches, embryonic structures that exhibit …

[HTML][HTML] A global control region defines a chromosomal regulatory landscape containing the HoxD cluster

F Spitz, F Gonzalez, D Duboule - Cell, 2003 - cell.com
During limb development, coordinated expression of several Hoxd genes is required in
presumptive digits. We searched for the underlying control sequences upstream from the …

Possible involvement of SINEs in mammalian-specific brain formation

T Sasaki, H Nishihara, M Hirakawa… - Proceedings of the …, 2008 - National Acad Sciences
Retroposons, such as short interspersed elements (SINEs) and long interspersed elements
(LINEs), are the major constituents of higher vertebrate genomes. Although there are many …

Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor

S Ruf, O Symmons, VV Uslu, D Dolle, C Hot… - Nature …, 2011 - nature.com
We present here a Sleeping Beauty–based transposition system that offers a simple and
efficient way to investigate the regulatory architecture of mammalian chromosomes in vivo …

Regulatory roles of conserved intergenic domains in vertebrate Dlx bigene clusters

N Ghanem, O Jarinova, A Amores, Q Long… - Genome …, 2003 - genome.cshlp.org
Dlx homeobox genes of vertebrates are generally arranged as three bigene clusters on
distinct chromosomes. The Dlx1/Dlx2, Dlx5/Dlx6, and Dlx3/Dlx7 clusters likely originate from …

Dlx3 is a crucial regulator of hair follicle differentiation and cycling

J Hwang, T Mehrani, SE Millar, MI Morasso - 2008 - journals.biologists.com
Dlx homeobox transcription factors regulate epidermal, neural and osteogenic cellular
differentiation. Here, we demonstrate the central role of Dlx3 as a crucial transcriptional …

A novel olfactory receptor gene family in teleost fish

LR Saraiva, SI Korsching - Genome research, 2007 - genome.cshlp.org
While for two of three mammalian olfactory receptor families (OR and V2R) ortholog teleost
families have been identified, the third family (V1R) has been thought to be represented by a …