Pyrazine is one of the important class of heterocyclic compounds that can be obtained
naturally or synthesized chemically. Pyrazine ring has got importance in exhibiting various …

The properties of pyrimidine and pyrazine derivatives responsible for the existence of
antituberculosis activity are considered. Examples of synthesis and biological activity of the …

Tuberculosis (TB), an airborne disease caused by Mycobacterium tuberculosis, has infected
millions of people and been responsible for their deaths. Toward the anti‐TB endeavor, the …

Two series of quinoline-based compounds were designed, synthesised and evaluated for
anti-tubercular activity against Mycobacterium tuberculosis H 37 Rv (ATCC 27294 strain). A …

Using density functional theory technique in the B3LYP approximation and cc-pVDZ (5D, 7F)
basis set, the molecular structural parameters and vibrational wave numbers of two …

The solubility of pyrazinamide in ten solvents (water, methanol, ethanol, 1-propanol, 2-
propanol, 1-butanol, 2-butanol, acetone, acetonitrile and ethyl acetate) at temperatures …

Aminodehalogenation of 3-chloropyrazine-2-carboxamide with variously substituted
benzylamines yielded a series of fifteen 3-benzylaminopyrazine-2-carboxamides. Four …

5-Chloropyrazinamide (5-Cl-PZA) is an inhibitor of mycobacterial fatty acid synthase I with a
broad spectrum of antimycobacterial activity in vitro. Some N-phenylpyrazine-2 …

Abstract The FT-IR and FT-Raman spectra of N-(3-iodo-4-methylphenyl) pyrazine-2-
carboxamide were recorded and the experimentally observed wavenumbers are compared …

The solubility values of pyrazinamide, isoniazid, and p-aminobenzoic acid in buffers (рН 2.0
and 7.4) and octanol were measured in the temperature range of 293.15 to 313.15 K. The …