The transient receptor potential vanilloid 1 and ankyrin 1 (TRPV1 and TRPA1, respectively)
channels are members of the TRP superfamily of structurally related, non‐selective cation …

A large body of evidence now exists to substantiate that the endocannabinoid, anandamide,
activates TRPV1 receptors. It is a low intrinsic efficacy TRPV1 agonist that behaves as a …

Antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body
temperature (T b) in laboratory animals and humans: most cause hyperthermia; some …

The vanilloid receptor 1 (VR1 or TRPV1) is a membrane-bound, nonselective cation channel
expressed by peripheral sensory neurons. TRPV1 antagonists produce antihyperalgesic …

Endovanilloids are defined as endogenous ligands and activators of transient receptor
potential (TRP) vanilloid type 1 (TRPV1) channels. The first endovanilloid to be identified …

Vanilloid receptor 1 (TRPV1), a membrane-associated cation channel, is activated by the
pungent vanilloid from chili peppers, capsaicin, and the ultra potent vanilloid from Euphorbia …

The development of antagonists of the transient receptor potential vanilloid-1 (TRPV1)
channel as pain therapeutics has revealed that these compounds cause hyperthermia in …

Capsaicin (CAP) is a spice-derived substance of the genus Capsicum, which has high
pungency and therapeutic potential. For many years, it has been considered only as an …

Vanilloid receptor type 1 (VR1)(TRPV1) is a ligand-gated ion channel expressed on sensory
nerves that responds to noxious heat, protons, and chemical stimuli such as capsaicin …

Vanilloid-subfamily TRP channels TRPV1-6 play important roles in various physiological
processes and are implicated in numerous human diseases. Advances in structural biology …