Rheumatoid arthritis (RA) remains a challenging chronic autoimmune disorder
characterized by persistent joint inflammation and damage. While modern regenerative …

MicroRNAs (miRNAs) are a group of small single strand and noncoding RNAs that regulate
several physiological and molecular signalling pathways. Alterations of miRNA expression …

Introduction The advent of anti-tumor necrosis factor alpha (anti-TNFα) drugs has
considerably improved medical management in rheumatoid arthritis (RA) patients, although …

Background Rheumatoid arthritis is a long-term, progressive autoimmune disease. It is
characterized by synovial hyperplasia leading to swelling, stiffness, and joint deformity in …

The contribution of pre-mRNA processing mechanisms to the regulation of immune
responses remains poorly studied despite emerging examples of their role as regulators of …

Objective Systemic juvenile idiopathic arthritis (JIA) is an inflammatory disease of childhood
in which cells of the monomyelocytoid lineage are thought to be key effector cells …

Background Gout is considered one of the most painful acute conditions caused by
deposition of monosodium urate (MSU) crystals within joints. Recent studies have shown …

Background: Understanding the roles of circulating microRNAs (miRNAs) can provide
important and novel information regarding disease pathogenesis and a patient's clinical …

Rationale: Rheumatoid arthritis (RA) is a prototype of inflammatory arthritis in which synovial
fibroblasts (SFs) play key roles in cartilage and bone destruction through tumor-like …

Background MicroRNAs (miRNAs) control multiple biological processes including the innate
immune responses by negative post-transcriptional regulation of gene expression. As there …