Burn injuries elicit a unique and dynamic stress response which can lead to burn injury
progression. Though neutrophils represent crucial players in the burn-induced …

Background The efficacy of neutrophil elastase inhibitor sivelestat in the treatment of acute
lung injury (ALI) and acute respiratory distress syndrome (ARDS) remains controversial. A …

Background Sivelestat is widely used in treating acute lung injury (ALI)/acute respiratory
distress syndrome (ARDS), although the clinical efficacy of sivelestat remains controversial …

Introduction Blast injuries are complex types of physical trauma resulting from direct or
indirect exposure to an explosion, which can be divided into four classes: primary …

Objectives: Infants with congenital heart disease frequently require cardiopulmonary bypass,
which causes systemic inflammation. The goal of this study was to determine if neutrophil …

While protective measures have been taken to mitigate injury to the thorax during a blast
exposure, primary blast lung injury (PBLI) is still evident in mounted/in vehicle cases during …

Background: Hydrogen has anti-inflammatory and antioxidant effects and is beneficial to
multiple organs. However, its effect on alveolar macrophage (AM) pyroptosis induced by …

Burn wound conversion is the observed process where superficial partial thickness burns
convert into deep partial or full thickness burn injuries. This conversion process often …

The objective of this study was to evaluate the histopathological effect of gas explosion on
rats, and to explore the metabolic alterations associated with gas explosion-induced acute …

Objective High vasopermeability and excessive inflammation following severe burns may
result in tissue edema, organ dysfunction and the loss of circulatory plasma volume, which …