Background/Aims: Although it is widely acknowledged that atherosclerosis is mainly a
chronic inflammatory process, in which both miR-29b and interleukin-6 (IL-6) play …

Цель: уточнить границы применения термина «эндотелиальная дисфункция» в
исследовательской и клинической работе. Результаты: понятие «эндотелиальная …

Background Apoptosis in vascular endothelial cells (VECs) are closely correlated to multiple
endotheliocyte-related cardiovascular diseases, for example atherosclerosis. Long non …

Acute myocardial ischaemia/reperfusion (MI/R) injury causes severe arrhythmias with a high
rate of lethality. Extensive research focus on endoplasmic reticulum (ER) stress and its …

Sulodexide (SDX) is a highly purified glycosaminoglycan with antithrombotic and
profibrinolytic properties and reported benefits in thrombotic and atherosclerotic vascular …

Localized scleroderma (morphea) is a chronic autoimmune disease of the connective tissue.
Its etiopathogenesis is unknown. Most often the disease affects the skin, but may also …

Sulodexide (SDX), a purified glycosaminoglycan mixture used to treat vascular diseases,
has been reported to exert endothelial protective effects against ischemic injury. However …

High pressure in the lower-limb veins is often associated with chronic venous insufficiency
and varicose veins (VVs), making it important to search for the mechanisms and agents that …

Results We found that after short-term OGD (1–3 h), the drug increased the expression of
both GSTP1 and Nrf2 mRNA/protein in HUVECs (p< 0.05), as determined by real-time PCR …

Abstract Background/Aims: Aging of the arterial endothelial cells results in the appearance
of their inflammatory phenotype, which may predispose patients to the acceleration of …