Linkage chemistry of S (VI) fluorides
D Zeng, WP Deng, X Jiang - Chemistry–A European Journal, 2023 - Wiley Online Library
Sulfur (VI)‐fluoride exchange linkage as a next generation of click chemistry was introduced
by Sharpless and coworkers in 2014. Distinguished from CuAAC, the SuFEx reaction …
by Sharpless and coworkers in 2014. Distinguished from CuAAC, the SuFEx reaction …
Click chemistry in the design of AIEgens for biosensing and bioimaging
The development of rapid, selective, and sensitive fluorescent sensors is essential for
visualizing and quantifying biological molecules and processes in vitro, ex vitro, and in vivo …
visualizing and quantifying biological molecules and processes in vitro, ex vitro, and in vivo …
Epigenetic analysis of cell-free DNA by fragmentomic profiling
Cell-free DNA (cfDNA) fragmentation patterns contain important molecular information
linked to tissues of origin. We explored the possibility of using fragmentation patterns to …
linked to tissues of origin. We explored the possibility of using fragmentation patterns to …
[HTML][HTML] Phage diversity in cell-free DNA identifies bacterial pathogens in human sepsis cases
NL Haddock, LJ Barkal, N Ram-Mohan, G Kaber… - Nature …, 2023 - nature.com
Bacteriophages, viruses that infect bacteria, have great specificity for their bacterial hosts at
the strain and species level. However, the relationship between the phageome and …
the strain and species level. However, the relationship between the phageome and …
Chronic graft-versus-host disease detected by tissue-specific cell-free DNA methylation biomarkers
B Avni, D Neiman, E Shaked… - The Journal of …, 2024 - Am Soc Clin Investig
BACKGROUND. Accurate detection of graft-versus-host disease (GVHD) is a major
challenge in the management of patients undergoing hematopoietic stem cell …
challenge in the management of patients undergoing hematopoietic stem cell …
Ethene‐1, 1‐disulfonyl Difluoride (EDSF) for SuFEx Click Chemistry: Synthesis of SuFExable 1, 1‐Bissulfonylfluoride Substituted Cyclobutene Hubs
We present the synthesis of 1, 1‐bis (fluorosulfonyl)‐2‐(pyridin‐1‐ium‐1‐yl) ethan‐1‐ide, a
bench‐stable precursor to ethene‐1, 1‐disulfonyl difluoride (EDSF). The novel SuFEx …
bench‐stable precursor to ethene‐1, 1‐disulfonyl difluoride (EDSF). The novel SuFEx …
Plasma cell-free RNA signatures of inflammatory syndromes in children
CJ Loy, V Servellita, A Sotomayor-Gonzalez… - Proceedings of the …, 2024 - pnas.org
Inflammatory syndromes, including those caused by infection, are a major cause of hospital
admissions among children and are often misdiagnosed because of a lack of advanced …
admissions among children and are often misdiagnosed because of a lack of advanced …
Biomarkers for early complications post hematopoietic cell transplantation: Insights and challenges
B Balakrishnan, UP Kulkarni, AA Pai… - Frontiers in …, 2023 - frontiersin.org
Hematopoietic cell transplantation is an established curative treatment option for various
hematological malignant, and non-malignant diseases. However, the success of HCT is still …
hematological malignant, and non-malignant diseases. However, the success of HCT is still …
Modular synthesis of functional libraries by accelerated SuFEx click chemistry
Accelerated SuFEx Click Chemistry (ASCC) is a powerful method for coupling aryl and alkyl
alcohols with SuFEx-compatible functional groups. With its hallmark favorable kinetics and …
alcohols with SuFEx-compatible functional groups. With its hallmark favorable kinetics and …
A hitchhiker's guide to cell-free DNA biology
F Mouliere - Neuro-oncology advances, 2022 - academic.oup.com
Liquid biopsy provides a noninvasive window to the cancer genome and physiology. In
particular, cell-free DNA (cfDNA) is a versatile analyte for guiding treatment, monitoring …
particular, cell-free DNA (cfDNA) is a versatile analyte for guiding treatment, monitoring …