Cancer stem cells (CSCs) are heterogeneous, possess self-renewal attributes, and
orchestrate important crosstalk in tumors. We propose that the CSC state represents" …

Biliary tract cancers (BTCs) are a group of rare and aggressive malignancies that arise in the
biliary tree within and outside the liver. Beyond surgical resection, which is beneficial for …

Increased cancer stem cell content during development of resistance to tamoxifen in breast
cancer is driven by multiple signals, including Sox2-dependent activation of Wnt signalling …

To discover novel therapeutic targets for triple-negative breast cancer (TNBC) and cancer
stem cells (CSCs), we screened long non-coding RNAs (lncRNAs) most enriched in TNBCs …

Background: Microplastics (MPs) are a new global environmental threat. Previously, we
showed the biodistribution of MPs using [64 Cu] polystyrene (PS) and PET in mice. Here, we …

Over a decade of research has confirmed the critical role of cancer stem-like cells (CSCs) in
tumor initiation, chemoresistance, and metastasis. Increasingly, CSC hierarchies have …

Simple Summary Aldehyde dehydrogenase 1A3 (ALDH1A3) is the primary cause of the high
ALDH activity associated with cancer stem cell (CSC) populations in multiple cancers and its …

Cells with high CD44 but low CD24 expression (CD44high/CD24−/low) and high aldehyde
dehydrogenase activity (ALDHbr) are widely considered to be drivers of metastasis, therapy …

High aldehyde dehydrogenase (ALDH) activity is a metabolic feature of adult stem cells and
various cancer stem cells (CSCs). The ALDEFLUOR system is currently the most commonly …

Aldehyde dehydrogenase (ALDH) activity is commonly used as a marker to identify cancer
stem-like cells. The three ALDH1A isoforms have all been individually implicated in cancer …