Glioblastoma (GBM) is the most deadly type of malignant brain tumor, despite extensive
molecular analyses of GBM cells. In recent years, the tumor microenvironment (TME) has …

Glioblastoma (GBM) is the most aggressive and common form of primary brain cancer.
Several decades of research have provided great insight into GBM progression; however …

Glioblastoma (GBM) is a devastating and incurable brain tumour, with a median overall
survival of fifteen months,. Identifying the cell of origin that harbours mutations that drive …

Neural stem cells (NSCs) are self-renewing, multipotent cells which give rise to all
components of the central nervous system (CNS) during embryogenesis, but also activate in …

As most common primary brain cancer, glioblastoma is also the most aggressive and
malignant form of cancer in the adult central nervous system. Glioblastomas are genetic and …

Both in adult and children, high-grade gliomas (WHO grades III and IV) account for a high
proportion of death due to cancer. This poor prognosis is a direct consequence of tumor …

Life expectancy of patients treated for brain tumors has lengthened due to the therapeutic
improvements. Cognitive impairment has been described following brain radiotherapy, but …

Radiomics is an emerging discipline that aims to make intelligent predictions and derive
medical insights based on quantitative features extracted from medical images as a means …

Background. The current standard of care of glioblastoma, the most common primary brain
tumor in adults, has remained unchanged for over a decade. Nevertheless, some …

As many countries face an ageing population, the number of older patients with
glioblastoma (GB) is increasing. Thus, there is an urgent need for prognostic models to aid …