Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

Metabolomics is a branch of chemistry in which endogenous metabolites present in a
biological sample are accessed and efforts are made for their identification as well as …

Breast cancer brain metastases remain largely incurable. Although several mouse models
have been developed to investigate the genes and mechanisms regulating breast cancer …

Longitudinal in vivo proton magnetic resonance spectroscopy (1H-MRS) and
immunohistochemistry were performed to investigate the tissue degeneration in …

Background Establishing a large rodent model of brain metastasis that can be monitored
using clinically relevant magnetic resonance imaging (MRI) techniques is challenging. Non …

NMR spectroscopy has become one of the preferred analytical techniques for metabolomics
studies due to its inherent nondestructive nature, ability to identify and quantify metabolites …

The translation of results from the preclinical to the clinical setting is often anything other
than straightforward. Indeed, ideas and even very intriguing results obtained at all levels of …

Classifiers based on statistical pattern recognition analysis of MRSI data are becoming
important tools for the non-invasive diagnosis of human brain tumors. Here we investigate …

Brain metastasis (BM) is a major cause of cancer patient morbidity. Clinical magnetic
resonance imaging (MRI) and positron emission tomography (PET) represent important …

Currently, survival of breast cancer patients with brain metastasis ranges from 2 to 16
months. In experimental brain metastasis studies, only 10% of lesions with the highest …