Compression physics in the formulation development of tablets

S Patel, AM Kaushal, AK Bansal - Critical Reviews™ in …, 2006 - dl.begellhouse.com
The advantages of high-precision dosing, manufacturing efficiency, and patient compliance
make tablets the most popular dosage forms. Compaction, an essential manufacturing step …

Quantification of the compactibility of pharmaceutical powders

JM Sonnergaard - European Journal of Pharmaceutics and …, 2006 - Elsevier
The purpose of this study is to investigate and to quantify the compactibility of
pharmaceutical powders by a simple linear relationship between the diametral compressive …

How do roll compaction/dry granulation affect the tableting behaviour of inorganic materials? Comparison of four magnesium carbonates

F Freitag, P Kleinebudde - European journal of pharmaceutical sciences, 2003 - Elsevier
The effect of roll compaction/dry granulation on the particle and bulk material characteristics
of different magnesium carbonates was evaluated. The flowability of all materials could be …

Understanding size enlargement and hardening of granules on tabletability of unlubricated granules prepared by dry granulation

S Patel, S Dahiya, CC Sun, AK Bansal - Journal of pharmaceutical …, 2011 - Elsevier
The mechanism of loss of “reworkability” or tabletability of dry granulated microcrystalline
cellulose (MCC) was investigated in relation to both granule size enlargement and granule …

The effect of pre-compaction on properties of Mg/SiC nanocomposites compacted at high strain rates

GH Majzoobi, K Rahmani, M Kashfi - Journal of Stress Analysis, 2020 - jrstan.basu.ac.ir
The effect of pre-compaction on mechanical properties of Mg/SiC nanocomposites prepared
through dynamic compaction was investigated. The dynamic compactions were carried out …

Compression and compaction

SW Hoag, VS Dave… - … dosage forms-tablets, 2008 - api.taylorfrancis.com
A tablet is formed by reducing the volume of a set of autonomous particles until they
areconsolidated into a solid body; a tablet is manufactured by placing a powder in a die …

Lubricant sensitivity in function of paddle movement in the forced feeder of a high-speed tablet press

E Peeters, V Vanhoorne, C Vervaet… - Drug Development and …, 2016 - Taylor & Francis
Context: The negative impact of magnesium stearate (MgSt) on the hardness of tablets is a
well-known phenomenon, but the influence of paddle movement in the forced feeder on the …

Predictive and correlative techniques for the design, optimisation and manufacture of solid dosage forms

IJ Hardy, WG Cook - Journal of pharmacy and pharmacology, 2003 - Wiley Online Library
There is much interest in predicting the properties of pharmaceutical dosage forms from the
properties of the raw materials they contain. Achieving this with reasonable accuracy would …

Compression forces and amount of outer coating layer affecting the time‐controlled disintegration of the compression‐coated tablets prepared by direct compression …

KH Lin, SY Lin, MJ Li - Journal of pharmaceutical sciences, 2001 - Elsevier
The influence of compression force to inner core tablet or to outer coating layer of the
compression‐coated tablet on the function of time‐controlled disintegration was …

Structural and functional analysis of a new co-processed tableting excipient for food compaction processes

R Rösemeier-Scheumann, L Wagner, U Bobe… - Journal of Food …, 2024 - Elsevier
Food compacts are convenient to industry and customers and must primarily possess a
sufficient strength to withstand packaging processing and customer handling. In contrast to …