Chronic ethanol consumption: from neuroadaptation to neurodegeneration

F Fadda, ZL Rossetti - Progress in neurobiology, 1998 - Elsevier
In this review first we evaluate evidence on the role of the neurobiological alterations
induced by chronic ethanol consumption in the development of ethanol tolerance …

Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study

A Topiwala, CL Allan, V Valkanova, E Zsoldos… - bmj, 2017 - bmj.com
Objectives To investigate whether moderate alcohol consumption has a favourable or
adverse association or no association with brain structure and function. Design …

Regulation of NMDA receptors by ethanol

M Kumari, MK Ticku - Progress in Drug research, 2000 - Springer
NMDA receptors are glutamate-gated ion channels, mediating excitatory neurotransmission
in the brain. These widely distributed receptors are known to play a role in neuronal …

Glial cell loss in the hippocampus of alcoholics

L Korbo - Alcoholism: Clinical and Experimental Research, 1999 - Wiley Online Library
Alcohol abuse is often accompanied by cognitive impairment. Memory and concentration
problems, especially, are described in neuropsychologically tested abstinent alcoholics …

Selective vulnerability of the hippocampal pyramidal neurons to hypothyroidism in male and female rats

MD Madeira, N Sousa… - Journal of …, 1992 - Wiley Online Library
Thyroid hormone deficiency has long been considered to affect profoundly such cognitive
functions as learning and memory, which are known to depend on the structural integrity of …

Effect of alcohol on hippocampal-dependent plasticity and behavior: role of glutamatergic synaptic transmission

RG Mira, M Lira, C Tapia-Rojas… - Frontiers in behavioral …, 2020 - frontiersin.org
Problematic alcohol drinking and alcohol dependence are an increasing health problem
worldwide. Alcohol abuse is responsible for approximately 5% of the total deaths in the …

The reaction of astrocytes and neurons in the hippocampus of adult rats during chronic ethanol treatment and correlations to behavioral impairments

H Franke, H Kittner, P Berger, K Wirkner, J Schramek - Alcohol, 1997 - Elsevier
Chronic ethanol treatment of Wistar rats to 10%(v/v) ethanol over a period of 4, 12, and 36
weeks produced distinct alterations of the glial fibrillary acidic protein immunoreactivity …

Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity …

MD Madeira, JP Andrade, AR Lieberman… - Journal of …, 1997 - Soc Neuroscience
There is evidence that chronic ethanol treatment (CET) disrupts the biological rhythms of
various brain functions and behaviors. Because the suprachiasmatic nucleus (SCN) is …

Behavioral and neuroanatomical consequences of chronic ethanol intake and withdrawal

NV Lukoyanov, MD Madeira, MM Paula–Barbosa - Physiology & behavior, 1999 - Elsevier
We have examined if long-term (13 months) alcohol consumption and the same treatment
followed by a 6-week withdrawal period cause different neuropathological changes in rats …

Structural changes in the hippocampal formation after long‐term alcohol consumption and withdrawal in the rat

MM Paula‐Barbosa, F Brandao, MD Madeira… - …, 1993 - Wiley Online Library
The effects of long‐term alcohol consumption and withdrawal upon the structure of the rat
hippocampal formation were studied by applying morphometric methods to material …