Gut microbial metabolites as multi-kingdom intermediates

KA Krautkramer, J Fan, F Bäckhed - Nature Reviews Microbiology, 2021 - nature.com
The gut microbiota contributes to host physiology through the production of a myriad of
metabolites. These metabolites exert their effects within the host as signalling molecules and …

Origins of lifetime health around the time of conception: causes and consequences

TP Fleming, AJ Watkins, MA Velazquez, JC Mathers… - The Lancet, 2018 - thelancet.com
Parental environmental factors, including diet, body composition, metabolism, and stress,
affect the health and chronic disease risk of people throughout their lives, as captured in the …

Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child

PM Catalano, K Shankar - Bmj, 2017 - bmj.com
Obesity is the most common medical condition in women of reproductive age. Obesity during
pregnancy has short term and long term adverse consequences for both mother and child …

One-carbon metabolism: linking nutritional biochemistry to epigenetic programming of long-term development

CE Clare, AH Brassington, WY Kwong… - Annual review of …, 2019 - annualreviews.org
One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that
include the methionine and folate cycles that are central to cellular function, providing 1C …

African genetic diversity and adaptation inform a precision medicine agenda

L Pereira, L Mutesa, P Tindana, M Ramsay - Nature Reviews Genetics, 2021 - nature.com
The deep evolutionary history of African populations, since the emergence of modern
humans more than 300,000 years ago, has resulted in high genetic diversity and …

The International Federation of Gynecology and Obstetrics (FIGO) recommendations on adolescent, preconception, and maternal nutrition:" Think Nutrition First".

MA Hanson, A Bardsley, LM De-Regil, SE Moore… - 2015 - cabidigitallibrary.org
This document is directed at a range of stakeholders with the intention of highlighting the
central role that nutrition has on adolescent, maternal, and infant well-being. This is an area …

[HTML][HTML] DNA methylation signatures link prenatal famine exposure to growth and metabolism

EW Tobi, JJ Goeman, R Monajemi, H Gu… - Nature …, 2014 - nature.com
Periconceptional diet may persistently influence DNA methylation levels with phenotypic
consequences. However, a comprehensive assessment of the characteristics of prenatal …

[HTML][HTML] Biomarkers of nutrition and health: new tools for new approaches

C Picó, F Serra, AM Rodríguez, J Keijer, A Palou - Nutrients, 2019 - mdpi.com
A main challenge in nutritional studies is the valid and reliable assessment of food intake, as
well as its effects on the body. Generally, food intake measurement is based on self-reported …

Epigenetics and the environment: emerging patterns and implications

R Feil, MF Fraga - Nature reviews genetics, 2012 - nature.com
Epigenetic phenomena in animals and plants are mediated by DNA methylation and stable
chromatin modifications. There has been considerable interest in whether environmental …

DNA methylation markers in obesity, metabolic syndrome, and weight loss

M Samblas, FI Milagro, A Martínez - Epigenetics, 2019 - Taylor & Francis
The fact that not all individuals exposed to the same environmental risk factors develop
obesity supports the hypothesis of the existence of underlying genetic and epigenetic …