Sepsis is a highly complex and lethal syndrome with highly heterogeneous clinical
manifestations that makes it difficult to detect and treat. It is also one of the major and most …

The immunological hallmarks of sepsis include the inflammation-mediated cytokine storm,
apoptosis-driven lymphopenia, and prolonged immunoparalysis. Although early clinical …

Purpose There is limited knowledge on how the source of infection impacts the host
response to sepsis. We aimed to compare the host response in sepsis patients with a single …

Background Sepsis is a life-threatening organ dysfunction caused by a dysregulated host
response to infection, with extremely high mortality. Notably, sepsis is a heterogeneous …

We carried out a prospective observational study to evaluate whether Monocyte Distribution
Width (MDW) may play a role in identifying patients with sepsis in comparison with …

Community-acquired pneumonia as an emergency condition : Current Opinion in Critical Care
Community-acquired pneumonia as an emergency condition : Current Opinion in Critical Care …

Septic cardiomyopathy (SCM) is a common complication of sepsis contributing to high
mortality rates. Its pathophysiology involves complex factors, including inflammatory …

Septic shock is a leading cause of hospitalisation, morbidity, and mortality for children
worldwide. In 2020, the paediatric Surviving Sepsis Campaign (SSC) issued evidence …

Prolonged immunosuppression is increasingly recognized as the major cause of late phase
and long-term mortality in sepsis. Numerous murine models with different paradigms, such …

Sepsis is a highly lethal syndrome with heterogeneous clinical manifestation that can be
hard to identify and treat. Early diagnosis and appropriate treatment are critical to reduce …