Post-tuberculosis lung disease: clinical review of an under-recognised global challenge

BW Allwood, A Byrne, J Meghji, A Rachow… - Respiration, 2021 - karger.com
An estimated 58 million people have survived tuberculosis since 2000, yet many of them will
suffer from post-tuberculosis lung disease (PTLD). PTLD results from a complex interplay …

Post-tuberculosis lung impairment: systematic review and meta-analysis of spirometry data from 14 621 people

O Ivanova, VS Hoffmann, C Lange… - European …, 2023 - Eur Respiratory Soc
Background A substantial proportion of tuberculosis patients remain with pulmonary
symptoms and reduced physical capacity despite successful treatment. We performed a …

Post-TB health and wellbeing

R Nightingale, F Carlin, J Meghji… - … of Tuberculosis and …, 2023 - ingentaconnect.com
TB affects around 10.6 million people each year and there are now around 155 million TB
survivors. TB and its treatments can lead to permanently impaired health and wellbeing. In …

The burden and determinants of post-TB lung disease

SG Mpagama, KS Msaji, O Kaswaga… - … of Tuberculosis and …, 2021 - ingentaconnect.com
BACKGROUND: Post-TB lung disease (PTLD) is an important but under-recognised chronic
respiratory disease in high TB burden settings such as Tanzania. METHODS: This was a …

Residual respiratory disability after successful treatment of pulmonary tuberculosis: a systematic review and meta-analysis

J Taylor, ML Bastos, S Lachapelle-Chisholm… - …, 2023 - thelancet.com
Background Pulmonary tuberculosis (PTB) can result in long-term health consequences,
even after successful treatment. We conducted a systematic review and meta-analysis to …

Persistent chronic respiratory symptoms despite TB cure is poorly correlated with lung function

BW Allwood, M Stolbrink, N Baines… - … of Tuberculosis and …, 2021 - ingentaconnect.com
BACKGROUND: Persistent respiratory symptoms and lung function deficits are common
after patients with TB. We aimed to define the burden of post-TB lung disease (PTLD) and …

Effect of digital medication event reminder and monitor-observed therapy vs standard directly observed therapy on health-related quality of life and catastrophic costs …

T Manyazewal, Y Woldeamanuel, A Fekadu… - JAMA Network …, 2022 - jamanetwork.com
Importance Little is known about whether digital adherence technologies are economical for
patients with tuberculosis (TB) in resource-constrained settings. Objective To test the …

COVID-19 and tuberculosis: Unveiling the dual threat and shared solutions perspective

R Cioboata, V Biciusca, M Olteanu… - Journal of Clinical …, 2023 - mdpi.com
The year 2020 will likely be remembered as the year dominated by COVID-19, or
coronavirus disease. The emergence of severe acute respiratory syndrome coronavirus 2 …

Platelet activation and the immune response to tuberculosis

DE Kirwan, DLW Chong, JS Friedland - Frontiers in Immunology, 2021 - frontiersin.org
In 2019 10 million people developed symptomatic tuberculosis (TB) disease and 1.2 million
died. In active TB the inflammatory response causes tissue destruction, which leads to both …

TB morbidity estimates overlook the contribution of post-TB disability: evidence from urban Malawi

EM Tomeny, R Nightingale, B Chinoko… - BMJ Global …, 2022 - gh.bmj.com
Introduction Despite growing evidence of the long-term impact of tuberculosis (TB) on quality
of life, Global Burden of Disease (GBD) estimates of TB-related disability-adjusted life years …