Biodegradable materials, including natural and synthetic polymers and hydrolyzable metals,
constitute the main components of temporary, implantable medical devices. Besides the …

Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Peripheral nerve injury (PNI) is currently recognized as one of the most significant public
health issues and affects the general well‐being of millions of individuals worldwide …

The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

The strategies concerning modification of the complex immune pathological inflammatory
environment during acute spinal cord injury remain oversimplified and superficial. Inspired …

The immune system plays a central role in tissue repair and regeneration. Indeed, the
immune response to tissue injury is crucial in determining the speed and the outcome of the …

Organ and tissue loss through disease and injury motivate the development of therapies that
can regenerate tissues and decrease reliance on transplantations. Regenerative medicine …

Neuroinflammation has positive and negative effects. This review focuses on the roles of
macrophage in the PNS. Transection of PNS axons leads to degeneration and clearance of …

In normal tissue repair, macrophages exhibit a pro-inflammatory phenotype (M1) at early
stages and a pro-healing phenotype (M2) at later stages. We have previously shown that M1 …

The peripheral nervous system (PNS) has remarkable regenerative abilities after injury.
Successful PNS regeneration relies on both injured axons and non-neuronal cells, including …