In obese individuals, atherogenic dyslipidemia is a very common and important factor in the
increased risk of cardiovascular disease. Adiposity-associated dyslipidemia is characterized …

Obesity is characterized by increased storage of fatty acids in an expanded adipose tissue
mass and is closely associated with the development of insulin resistance in peripheral …

During the last decades, research on adipose tissues has spread in parallel with the
extension of obesity. Several observations converged on the idea that adipose tissues are …

OBJECTIVE Comprehensive proteomic profiling of the human adipocyte secretome
identified dipeptidyl peptidase 4 (DPP4) as a novel adipokine. This study assessed the …

Context: Adipocytes are known to release a variety of factors that may contribute to the
proinflammatory state characteristic for obesity. This secretory function is considered to …

OBJECTIVE Chemerin is an adipokine that affects adipogenesis and glucose homeostasis
in adipocytes and increases with BMI in humans. This study was aimed at investigating the …

AMPK (AMP-activated protein kinase) is a key regulator of cellular and whole-body energy
balance. AMPK phosphorylates and regulates many proteins concerned with nutrient …

Purpose: To review recent advances in the pathophysiology and potential clinical
applications of leptin, an adipose tissue-derived hormone. Data Sources: A MEDLINE …

Over the past decade and a half it has become increasingly clear that adipose tissue is a
much more complex organ than was initially considered and that its metabolic functions …

Upper body obesity is a risk factor for type 2 diabetes. Little is known about the regulation of
body fat distribution, but leptin may be involved. This study examined the secretion of leptin …