Copper complexes as anticancer agents

C Marzano, M Pellei, F Tisato… - Anti-Cancer Agents in …, 2009 - ingentaconnect.com
Metal-based antitumor drugs play a relevant role in antiblastic chemotherapy. Cisplatin is
regarded as one of the most effective drugs, even if severe toxicities and drug resistance …

Biological importance of imidazole nucleus in the new millennium

B Narasimhan, D Sharma, P Kumar - Medicinal Chemistry Research, 2011 - Springer
Imidazole nucleus is a constituent of many bioactive heterocyclic compounds that are of
wide interest because of their diverse biological and clinical applications. This created …

Syntheses and evaluation of antioxidant activity of sydnonyl substituted thiazolidinone and thiazoline derivatives

MH Shih, FY Ke - Bioorganic & medicinal chemistry, 2004 - Elsevier
3-Aryl-4-formylsydnone 4′-phenylthiosemicarbazones (3a–d) and 3-aryl-4-formylsydnone
thiosemicarbazones (3e–h), which are precursors of 3-aryl-4-heterocyclic sydnones, are …

Coordination chemistry of thiazoles, isothiazoles and thiadiazoles

LMT Frija, AJL Pombeiro, MN Kopylovich - Coordination Chemistry …, 2016 - Elsevier
Thiazole derived compounds have great potential in medicinal-and agro-chemistries,
catalysis, cosmetic industry, corrosion protection, light harvesting, production of light-emitting …

DNA Binding Studies of Novel Copper(II) Complexes Containing l-Tryptophan as Chiral Auxiliary:  In Vitro Antitumor Activity of Cu−Sn2 Complex in Human …

M Chauhan, K Banerjee, F Arjmand - Inorganic chemistry, 2007 - ACS Publications
Novel trinuclear complexes C23H31N6O6CuSn2Cl5 [1], C23H31N6O6CuZr2Cl5 [2],
C23H31N6O6ZnSn2Cl5 [3], and C23H31N6O6ZnZr2Cl5 [4] were synthesized and …

Reversible coordinative bonds in molecular recognition

M Kruppa, B König - Chemical reviews, 2006 - ACS Publications
Metal complexes with open coordination sites have found wide use in molecular recognition.
They serve as binding sites in the development of chemosensors, 1 to study metalloenzyme …

Antitumor activity of Pt (II), Ru (III) and Cu (II) complexes

K Gałczyńska, Z Drulis-Kawa, M Arabski - Molecules, 2020 - mdpi.com
Metal complexes are currently potential therapeutic compounds. The acquisition of
resistance by cancer cells or the effective elimination of cancer-affected cells necessitates a …

Copper (II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole: synthesis, characterization, antiproliferative and …

AT Chaviara, PJ Cox, KH Repana, RM Papi… - Journal of inorganic …, 2004 - Elsevier
A new series of coordination compounds of the starting materials [Cu (dienX2Y2)] and their
adducts [Cu (dienXXY2)(2a-5mt)](where dien= diethylenetriamine, dienXX= Schiff bases of …

Synthesis and biological evaluation of some 2, 4, 5‐trisubstituted thiazole derivatives as potential antimicrobial and anticancer agents

MS Al‐Saadi, HM Faidallah… - Archiv der Pharmazie …, 2008 - Wiley Online Library
We report on the synthesis and biological evaluation of two series of 2, 4, 5‐polysubstituted
thiazoles comprising the acid hydrazide functionality and some derived pharmacophores …

Thiazoles and thiazolidinones as antioxidants

AA Geronikaki, EP Pitta… - Current Medicinal …, 2013 - ingentaconnect.com
Antioxidants are of great interest because of their involvement in important biological and
industrial processes. According to Halliwell antioxidants are substances that at low …