Catharanthus roseus (L.) G. Don: A review of its ethnobotany, phytochemistry, ethnopharmacology and toxicities
Ethnopharmacological relevance Catharanthus roseus (L.) G. Don is a well known
medicinal plant belonging to family Apocynaceae that have been traditionally used as …
medicinal plant belonging to family Apocynaceae that have been traditionally used as …
Astrocyte apoptosis: implications for neuroprotection
K Takuma, A Baba, T Matsuda - Progress in neurobiology, 2004 - Elsevier
Astrocytes, the most abundant glial cell types in the brain, provide metabolic and trophic
support to neurons and modulate synaptic activity. Accordingly, impairment in these …
support to neurons and modulate synaptic activity. Accordingly, impairment in these …
An update on vinpocetine: New discoveries and clinical implications
Y Zhang, J Li, C Yan - European journal of pharmacology, 2018 - Elsevier
Vinpocetine, a derivative of the alkaloid vincamine, has been clinically used in many
countries for treatment of cerebrovascular disorders such as stroke and dementia for more …
countries for treatment of cerebrovascular disorders such as stroke and dementia for more …
In situ measurement of solute transport in the bone lacunar-canalicular system
L Wang, Y Wang, Y Han… - Proceedings of the …, 2005 - National Acad Sciences
Solute transport through the bone lacunar-canalicular system is believed to be essential for
osteocyte survival and function but has proved difficult to measure. We report an approach …
osteocyte survival and function but has proved difficult to measure. We report an approach …
Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy
SA Zaitone, DM Abo-Elmatty, AA Shaalan - … Biochemistry and Behavior, 2012 - Elsevier
Although the mechanisms of neurodegeneration in Parkinson's disease are not fully
understood, mitochondrial dysfunction, oxidative stress and environmental toxins may be …
understood, mitochondrial dysfunction, oxidative stress and environmental toxins may be …
Neuroprotective effects of novel nanosystems simultaneously loaded with vinpocetine and piracetam after intranasal administration
M Nasr, SA Wahdan - Life sciences, 2019 - Elsevier
Aims The study aim was to test the efficacy of a novel created hybrid nanosystem compared
to other nanosystems in treatment of scopolamine induced memory impairment. Main …
to other nanosystems in treatment of scopolamine induced memory impairment. Main …
Cure of alzheimer's dementia requires addressing all of the affected brain cell types
J Fessel - Journal of Clinical Medicine, 2023 - mdpi.com
Multiple genetic, metabolic, and environmental abnormalities are known to contribute to the
pathogenesis of Alzheimer's dementia (AD). If all of those abnormalities were addressed it …
pathogenesis of Alzheimer's dementia (AD). If all of those abnormalities were addressed it …
Eburnamine derivatives and the brain
A Vas, B Gulyas - Medicinal research reviews, 2005 - Wiley Online Library
The Apocynaceae plant family contains a great number of so called eburnamine–vincamine
alkaloids. Quite a few of these alkaloids exert varied pharmacological activities on the cell …
alkaloids. Quite a few of these alkaloids exert varied pharmacological activities on the cell …
Piracetam improves mitochondrial dysfunction following oxidative stress
U Keil, I Scherping, S Hauptmann… - British journal of …, 2006 - Wiley Online Library
Mitochondrial dysfunction including decrease of mitochondrial membrane potential and
reduced ATP production represents a common final pathway of many conditions associated …
reduced ATP production represents a common final pathway of many conditions associated …
Effect of piracetam, vincamine, vinpocetine, and donepezil on oxidative stress and neurodegeneration induced by aluminum chloride in rats
OME Abdel-Salam, SM Hamdy, SAM Seadawy… - Comparative Clinical …, 2016 - Springer
In this study, we investigated the effects of the memory-enhancing drugs piracetam,
vincamine, and vinpocetine or the cholinesterase inhibitor donepezil on the development of …
vincamine, and vinpocetine or the cholinesterase inhibitor donepezil on the development of …