Cancer metabolomic markers in urine: evidence, techniques and recommendations

SS Dinges, A Hohm, LA Vandergrift, J Nowak… - Nature reviews …, 2019 - nature.com
Urinary tests have been used as noninvasive, cost-effective tools for screening, diagnosis
and monitoring of diseases since ancient times. As we progress through the 21st century …

Metabolomics technology and bioinformatics for precision medicine

RK Azad, V Shulaev - Briefings in bioinformatics, 2019 - academic.oup.com
Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small
group or even individual patients based on their genetics, environment and lifestyle …

Advances and perspectives in prostate cancer biomarker discovery in the last 5 years through tissue and urine metabolomics

AR Lima, J Pinto, F Amaro, ML Bastos, M Carvalho… - Metabolites, 2021 - mdpi.com
Prostate cancer (PCa) is the second most diagnosed cancer in men worldwide. For its
screening, serum prostate specific antigen (PSA) test has been largely performed over the …

[HTML][HTML] Analysis of urinary VOCs using mass spectrometric methods to diagnose cancer: A review

BRB da Costa, BS De Martinis - Clinical Mass Spectrometry, 2020 - Elsevier
The development of non-invasive screening techniques for early cancer detection is one of
the greatest scientific challenges of the 21st century. One promising emerging method is the …

Metabolomics biomarkers of prostate cancer: a systematic review

M Kdadra, S Höckner, H Leung, W Kremer, E Schiffer - Diagnostics, 2019 - mdpi.com
Prostate cancer (PCa) diagnosis with current biomarkers is difficult and often results in
unnecessary invasive procedures as well as over-diagnosis and over-treatment, highlighting …

Recent metabolomics analysis in tumor metabolism reprogramming

J Han, Q Li, Y Chen, Y Yang - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Metabolic reprogramming has been suggested as a hallmark of cancer progression.
Metabolomic analysis of various metabolic profiles represents a powerful and technically …

Metabolomics contributions to the discovery of prostate cancer biomarkers

N Gómez-Cebrián, A Rojas-Benedicto… - Metabolites, 2019 - mdpi.com
Prostate cancer (PCa) is one of the most frequently diagnosed cancers and a leading cause
of death among men worldwide. Despite extensive efforts in biomarker discovery during the …

A systematic review on metabolomics-based diagnostic biomarker discovery and validation in pancreatic cancer

NP Long, SJ Yoon, NH Anh, TD Nghi, DK Lim, YJ Hong… - Metabolomics, 2018 - Springer
Introduction Metabolomics is an emerging approach for early detection of cancer. Along with
the development of metabolomics, high-throughput technologies and statistical learning, the …

Untargeted metabolomics of prostate cancer zwitterionic and positively charged compounds in urine

A Cerrato, C Bedia, AL Capriotti, C Cavaliere… - Analytica Chimica …, 2021 - Elsevier
Prostate cancer, a leading cause of cancer-related deaths worldwide, principally occurs in
over 50-year-old men. Nowadays there is urgency to discover biomarkers alternative to …

Prospective serum metabolomic profiling of lethal prostate cancer

J Huang, AM Mondul, SJ Weinstein… - … journal of cancer, 2019 - Wiley Online Library
Impaired metabolism may play an important role in the pathogenesis of lethal prostate
cancer, yet there is a paucity of evidence regarding the association. We conducted a large …