Engineering approaches using antibody drug conjugates (ADCs) and bispecific antibodies
(bsAbs) are designed to overcome the limitations of conventional chemotherapies and …

Introduction lncRNAs are major players in regulatory networks orchestrating multiple cellular
functions, such as 3D chromosomal interactions, epigenetic modifications, gene expression …

The recent discovery of vast non-coding RNA-based regulatory networks that can be easily
modulated by nucleic acid-based drugs has opened numerous new therapeutic possibilities …

Antibody–drug conjugates (ADCs) have recently demonstrated impressive successes in
targeted drug delivery. Ultrasmall (< 10 nm) nanoparticle–drug conjugates (NDCs) share …

Targeted delivery and precise release of toxins is a prospective strategy for the treatment of
triple-negative breast cancer (TNBC), yet the flexibility to incorporate both properties …

Salinomycin (Sal) has attracted considerable attention in the field of tumor treatment,
especially for its inhibitory effect on cancer stem cells (CSCs) and drug-resistant tumor cells …

Breast cancer is a highly prevalent malignancy worldwide among women with an increasing
incidence in recent years. Triple-negative breast cancer (TNBC), a specific type of breast …

Recombinant adeno-associated viruses (rAAVs) have been extensively studied for decades
as carriers for delivering therapeutic genes. However, designing rAAV vectors with selective …

Artificially synthesized stimuli‐responsive biomolecules are attractive as molecular tools for
monitoring and modulating biological systems. In biological systems, redox stimuli are …

Trigger-activatable antisense oligonucleotides have been widely applied to regulate gene
function. Among them, caged cyclic antisense oligonucleotides (cASOs) maintain a specific …