Striatal cholinergic interneuron regulation and circuit effects
The striatum plays a central role in motor control and motor learning. Appropriate responses
to environmental stimuli, including pursuit of reward or avoidance of aversive experience all …
to environmental stimuli, including pursuit of reward or avoidance of aversive experience all …
Dopamine and addiction: what have we learned from 40 years of research
Among the neurotransmitters involved in addiction, dopamine (DA) is clearly the best known.
The critical role of DA in addiction is supported by converging evidence that has been …
The critical role of DA in addiction is supported by converging evidence that has been …
Therapeutic potential of α7 nicotinic acetylcholine receptors
D Bertrand, CHL Lee, D Flood, F Marger… - Pharmacological …, 2015 - ASPET
Progress in the fields of neuroscience and molecular biology has identified the forebrain
cholinergic system as being important in many higher order brain functions. Further analysis …
cholinergic system as being important in many higher order brain functions. Further analysis …
Molecular mechanisms underlying the neuroprotection of environmental enrichment in Parkinson's disease
TA Alarcón, SM Presti-Silva, APT Simões… - Neural Regeneration …, 2023 - journals.lww.com
Parkinson's disease is the most common movement disorder, affecting about 1% of the
population over the age of 60 years. Parkinson's disease is characterized clinically by …
population over the age of 60 years. Parkinson's disease is characterized clinically by …
Synaptic vesicle recycling pathway determines neurotransmitter content and release properties
In contrast to temporal coding by synaptically acting neurotransmitters such as glutamate,
neuromodulators such as monoamines signal changes in firing rate. The two modes of …
neuromodulators such as monoamines signal changes in firing rate. The two modes of …
Multiple nicotinic acetylcholine receptor subtypes in the mouse amygdala regulate affective behaviors and response to social stress
Electrophysiological and neurochemical studies implicate cholinergic signaling in the
basolateral amygdala (BLA) in behaviors related to stress. Both animal studies and human …
basolateral amygdala (BLA) in behaviors related to stress. Both animal studies and human …
Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA
Heroin, nicotine, cocaine, and MDMA are abused by billions of people. They are believed to
target midbrain dopamine neurons and/or serotonin neurons, but their effects on the …
target midbrain dopamine neurons and/or serotonin neurons, but their effects on the …
Food addiction and tobacco use disorder: common liability and shared mechanisms
As food addiction is being more commonly recognized within the scientific community,
parallels can be drawn between it and other addictive substance use disorders, including …
parallels can be drawn between it and other addictive substance use disorders, including …
High fructose corn syrup induces metabolic dysregulation and altered dopamine signaling in the absence of obesity
The contribution of high fructose corn syrup (HFCS) to metabolic disorder and obesity,
independent of high fat, energy-rich diets, is controversial. While high-fat diets are widely …
independent of high fat, energy-rich diets, is controversial. While high-fat diets are widely …
[HTML][HTML] Adolescent substance abuse, transgenerational consequences and epigenetics
H Salmanzadeh, SM Ahmadi-Soleimani… - Current …, 2021 - ncbi.nlm.nih.gov
Adolescence is the transitional period between childhood and adulthood and a critical
period in brain development. Adolescence in humans is also associated with increased …
period in brain development. Adolescence in humans is also associated with increased …