Genetic load: genomic estimates and applications in non-model animals

G Bertorelle, F Raffini, M Bosse, C Bortoluzzi… - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

Population genomics for wildlife conservation and management

PA Hohenlohe, WC Funk, OP Rajora - Molecular Ecology, 2021 - Wiley Online Library
Biodiversity is under threat worldwide. Over the past decade, the field of population
genomics has developed across nonmodel organisms, and the results of this research have …

The crucial role of genome-wide genetic variation in conservation

M Kardos, EE Armstrong… - Proceedings of the …, 2021 - National Acad Sciences
The unprecedented rate of extinction calls for efficient use of genetics to help conserve
biodiversity. Several recent genomic and simulation-based studies have argued that the …

The inflated significance of neutral genetic diversity in conservation genetics

JC Teixeira, CD Huber - Proceedings of the National …, 2021 - National Acad Sciences
The current rate of species extinction is rapidly approaching unprecedented highs, and life
on Earth presently faces a sixth mass extinction event driven by anthropogenic activity …

Inbreeding depression explains killer whale population dynamics

M Kardos, Y Zhang, KM Parsons, H Kang… - Nature Ecology & …, 2023 - nature.com
Understanding the factors that cause endangered populations to either grow or decline is
crucial for preserving biodiversity. Conservation efforts often address extrinsic threats, such …

Deleterious variation in natural populations and implications for conservation genetics

J Robinson, CC Kyriazis, SC Yuan… - Annual review of …, 2023 - annualreviews.org
Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …

Genetic rescue: A critique of the evidence supports maximizing genetic diversity rather than minimizing the introduction of putatively harmful genetic variation

K Ralls, P Sunnucks, RC Lacy, R Frankham - Biological Conservation, 2020 - Elsevier
Genetic rescue–ameliorating inbreeding depression and restoring genetic diversity of inbred
populations through gene flow-is valuable in wildlife conservation. Empirically validated …

Conservation of biodiversity in the genomics era

MA Supple, B Shapiro - Genome biology, 2018 - Springer
Abstract “Conservation genomics” encompasses the idea that genome-scale data will
improve the capacity of resource managers to protect species. Although genetic approaches …

Landscape genomics to enable conservation actions: the California Conservation Genomics Project

HB Shaffer, E Toffelmier, RB Corbett-Detig… - Journal of …, 2022 - academic.oup.com
Abstract The California Conservation Genomics Project (CCGP) is a unique, critically
important step forward in the use of comprehensive landscape genetic data to modernize …

The enormous repetitive Antarctic krill genome reveals environmental adaptations and population insights

C Shao, S Sun, K Liu, J Wang, S Li, Q Liu, BE Deagle… - Cell, 2023 - cell.com
Antarctic krill (Euphausia superba) is Earth's most abundant wild animal, and its enormous
biomass is vital to the Southern Ocean ecosystem. Here, we report a 48.01-Gb chromosome …