Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis of
tumor cells and their spread to various organs and tissues of body, providing undesirable …

Breast cancer has grown to be the second leading cause of cancer-related deaths in
women. Only a few treatment options are available for breast cancer due to the widespread …

Immune checkpoint therapy has achieved significant efficacy by blocking inhibitory
pathways to release the function of T lymphocytes. In the clinic, anti-programmed cell death …

Triple-negative breast cancer (TNBC) is a heterogeneous, recurring cancer associated with
a high rate of metastasis, poor prognosis, and lack of therapeutic targets. Although target …

Excessive activation of signal transducer and activator of transcription 3 (STAT3) signaling is
observed in a subset of many cancers, making activated STAT3 a highly promising potential …

Chemokines and their receptors show a strong relationship with poor clinical outcomes in
various cancers. However, their underlying mechanisms remain to be fully elucidated. In our …

Background Cell invasion is a hallmark of metastatic cancer, leading to unfavorable clinical
outcomes. In this study, we established two highly invasive lung cancer cell models (A549-i8 …

Recent advances in the understanding of the molecular mechanisms underlying cancer
progression have led to the development of novel therapeutic targeting strategies. Aberrant …

The thymus is a critical immune organ with endocrine and immune functions that plays
important roles in the physiological and pathological processes of the body. However, with …

Abstract Extracellular Vesicles (EVs) were isolated from human umbilical cord mesenchymal
stem cells (hUCMSCs) and were further encapsulated with cannabidiol (CBD) through …