[HTML][HTML] Tuberculosis and COVID-19 interaction: a review of biological, clinical and public health effects
Evidence is accumulating on the interaction between tuberculosis (TB) and COVID-19. The
aim of the present review is to report the available evidence on the interaction between …
aim of the present review is to report the available evidence on the interaction between …
[HTML][HTML] Epidemic and pandemic viral infections: impact on tuberculosis and the lung: A consensus by the World Association for Infectious Diseases and …
CWM Ong, GB Migliori, M Raviglione… - European …, 2020 - Eur Respiratory Soc
Major epidemics, including some that qualify as pandemics, such as severe acute
respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A …
respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A …
Studying neutrophil function in vitro: cell models and environmental factors
M Blanter, M Gouwy, S Struyf - Journal of inflammation research, 2021 - Taylor & Francis
Neutrophils are the most abundant immune cell type in the blood and constitute the first line
of defense against invading pathogens. Despite their important role in many diseases, they …
of defense against invading pathogens. Despite their important role in many diseases, they …
[HTML][HTML] Doxycycline host-directed therapy in human pulmonary tuberculosis
QH Miow, AF Vallejo, Y Wang, JM Hong… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Matrix metalloproteinases (MMPs) are key regulators of tissue destruction in
tuberculosis (TB) and may be targets for host-directed therapy. We conducted a phase II …
tuberculosis (TB) and may be targets for host-directed therapy. We conducted a phase II …
[HTML][HTML] High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis
Tuberculous meningitis (TB meningitis) is the most severe form of tuberculosis (TB),
requiring 12 months of multidrug treatment for cure, and is associated with high morbidity …
requiring 12 months of multidrug treatment for cure, and is associated with high morbidity …
[HTML][HTML] Neutrophils in tuberculosis: Cell biology, cellular networking and multitasking in host defense
RR Borkute, S Woelke, G Pei, A Dorhoi - International journal of molecular …, 2021 - mdpi.com
Neutrophils readily infiltrate infection foci, phagocytose and usually destroy microbes. In
tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis …
tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis …
[HTML][HTML] The impact of hypoxia on neutrophil degranulation and consequences for the host
KM Lodge, AS Cowburn, W Li, AM Condliffe - International journal of …, 2020 - mdpi.com
Neutrophils are key effector cells of innate immunity, rapidly recruited to defend the host
against invading pathogens. Neutrophils may kill pathogens intracellularly, following …
against invading pathogens. Neutrophils may kill pathogens intracellularly, following …
[HTML][HTML] Immunometabolism of Phagocytes During Mycobacterium tuberculosis Infection
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) remains as a leading killer
among infectious diseases worldwide. The nature of the host immune response dictates …
among infectious diseases worldwide. The nature of the host immune response dictates …
How neutrophil metabolism affects bacterial killing
JE Toller-Kawahisa, LAJ O'Neill - Open Biology, 2022 - royalsocietypublishing.org
Neutrophils are front line cells in immunity that quickly recognize and eliminate pathogens,
relying mainly on glycolysis to exert their killing functions. Even though investigations into …
relying mainly on glycolysis to exert their killing functions. Even though investigations into …
Interplay between extracellular matrix and neutrophils in diseases
Y Zhu, Y Huang, Q Ji, S Fu, J Gu, N Tai… - Journal of immunology …, 2021 - Wiley Online Library
The extracellular matrix (ECM) is a highly dynamic and complex network structure, which
exists in almost all tissues and is the microenvironment that cells rely on for survival. ECM …
exists in almost all tissues and is the microenvironment that cells rely on for survival. ECM …