[HTML][HTML] Tuberculosis and COVID-19 interaction: a review of biological, clinical and public health effects

D Visca, CWM Ong, S Tiberi, R Centis, L D'ambrosio… - Pulmonology, 2021 - Elsevier
Evidence is accumulating on the interaction between tuberculosis (TB) and COVID-19. The
aim of the present review is to report the available evidence on the interaction between …

[HTML][HTML] Epidemic and pandemic viral infections: impact on tuberculosis and the lung: A consensus by the World Association for Infectious Diseases and …

CWM Ong, GB Migliori, M Raviglione… - European …, 2020 - Eur Respiratory Soc
Major epidemics, including some that qualify as pandemics, such as severe acute
respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A …

Studying neutrophil function in vitro: cell models and environmental factors

M Blanter, M Gouwy, S Struyf - Journal of inflammation research, 2021 - Taylor & Francis
Neutrophils are the most abundant immune cell type in the blood and constitute the first line
of defense against invading pathogens. Despite their important role in many diseases, they …

[HTML][HTML] Doxycycline host-directed therapy in human pulmonary tuberculosis

QH Miow, AF Vallejo, Y Wang, JM Hong… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Matrix metalloproteinases (MMPs) are key regulators of tissue destruction in
tuberculosis (TB) and may be targets for host-directed therapy. We conducted a phase II …

[HTML][HTML] High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis

CA Ruiz-Bedoya, F Mota, EW Tucker… - The Journal of …, 2022 - Am Soc Clin Investig
Tuberculous meningitis (TB meningitis) is the most severe form of tuberculosis (TB),
requiring 12 months of multidrug treatment for cure, and is associated with high morbidity …

[HTML][HTML] Neutrophils in tuberculosis: Cell biology, cellular networking and multitasking in host defense

RR Borkute, S Woelke, G Pei, A Dorhoi - International journal of molecular …, 2021 - mdpi.com
Neutrophils readily infiltrate infection foci, phagocytose and usually destroy microbes. In
tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis …

[HTML][HTML] The impact of hypoxia on neutrophil degranulation and consequences for the host

KM Lodge, AS Cowburn, W Li, AM Condliffe - International journal of …, 2020 - mdpi.com
Neutrophils are key effector cells of innate immunity, rapidly recruited to defend the host
against invading pathogens. Neutrophils may kill pathogens intracellularly, following …

[HTML][HTML] Immunometabolism of Phagocytes During Mycobacterium tuberculosis Infection

R Kumar, P Singh, A Kolloli, L Shi, Y Bushkin… - Frontiers in molecular …, 2019 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) remains as a leading killer
among infectious diseases worldwide. The nature of the host immune response dictates …

How neutrophil metabolism affects bacterial killing

JE Toller-Kawahisa, LAJ O'Neill - Open Biology, 2022 - royalsocietypublishing.org
Neutrophils are front line cells in immunity that quickly recognize and eliminate pathogens,
relying mainly on glycolysis to exert their killing functions. Even though investigations into …

Interplay between extracellular matrix and neutrophils in diseases

Y Zhu, Y Huang, Q Ji, S Fu, J Gu, N Tai… - Journal of immunology …, 2021 - Wiley Online Library
The extracellular matrix (ECM) is a highly dynamic and complex network structure, which
exists in almost all tissues and is the microenvironment that cells rely on for survival. ECM …