Integrons are versatile gene acquisition systems commonly found in bacterial genomes.
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …

The integron is a powerful system which, by capturing, stockpiling, and rearranging new
functions carried by gene encoding cassettes, confers upon bacteria a rapid adaptation …

Mobile integrons are widespread genetic platforms that allow bacteria to modulate the
expression of antibiotic resistance cassettes by shuffling their position from a common …

The fitness effects of a mutation can depend, sometimes dramatically, on genetic
background; this phenomenon is often referred to as “epistasis.” Epistasis can have …

Horizontal gene transfer (HGT) is important for microbial evolution, but how evolutionary
forces shape the frequencies of horizontally transferred genetic variants in the absence of …

Integrons are genetic elements that are common in bacteria and are hotspots for genome
evolution. They facilitate the acquisition and reassembly of gene cassettes encoding a …

The spread of multidrug-resistant enterobacteria strains has posed a significant concern in
public health, especially when the strain harbors metallo-beta-lactamase (MBL)-encoding …

Integrons are genetic recombination platforms that enhance bacterial evolvability by
enabling the acquisition and differential expression of new genes. These genes are …

Integrons are mobile genetic elements that have played an important role in the
dissemination of antibiotic resistance. Under stress, the integron can generate combinatorial …

Vibrio cholerae is one of the deadliest pathogens in the history of humankind. It is the
causative agent of cholera, a disease characterized by a profuse and watery diarrhoea that …