Aging is a progressive loss of physiological function that increases risk of disease and
death. Among the many factors that contribute to human aging, mitochondrial dysfunction …

Mitochondria play an important role in the synthesis of steroid hormones, including the sex
hormone estrogen. Sex-specific regulation of these hormones is important for phenotypic …

Mitochondrial dynamics is a key process that modulates the ultrastructure, quality and
function of mitochondria. It is disrupted in numerous major neurodegenerative disorders …

Memory loss, often known as amnesia, is common in the elderly population and refers to
forgetting facts and experiences. It is associated with increased mitochondrial fragmentation …

This study aimed to determine the effects of mitotherapy on learning and memory and
hippocampal kynurenine (Kyn) pathway, mitochondria function, and dendritic arborization …

Repeated or prolonged early life exposure to anesthesia is neurotoxic in animals and
associated with neurocognitive impairment in later life in humans. We used electron …

Curcumin has been reported to have a therapeutic effect on Alzheimer's disease (AD), but
the specific mechanism remains to be elucidated. In the present research, we aimed to …

Altered cognition and inefficient learning and memory are hallmarks of brain aging resulting
from many small changes in the structure and function of neurons. One such change is a …

Studying the evolutionary history of gene families is a challenging and exciting task with a
wide range of implications. In addition to exploring fundamental questions about the origin …

Human/animal brain is a unique organ with substantially high metabolism but it contains no
energy reserve that is the reason it requires continuous supply of O2 and energy fluxes …