More and more systematic reviews of diagnostic test accuracy studies are being published,
but they can be methodologically challenging. In this paper, the authors present some of the …

Background Diagnostic evidence of the accuracy of a test for identifying a target condition of
interest can be estimated using systematic approaches following standardized …

Background Preterm birth is a major complication of pregnancy associated with perinatal
mortality and morbidity. Progesterone for the prevention of preterm labour has been …

OBJECTIVE: To estimate the association between inflammatory cytokines and the risk of
spontaneous preterm birth in asymptomatic women. DATA SOURCES: We searched …

There is not a single or combined screening method for preterm birth with high sensitivity
which will truly identify the women at risk for preterm birth while also with high specificity to …

Although preterm birth (at< 37 weeks' gestation) is sometimes indicated for the health of the
mother or her fetus, spontaneous preterm births occur as a consequence of spontaneous …

OBJECTIVE: The purpose of this study was to examine the diagnostic performance of
ultrasonographic measurement of the cervical length and vaginal fetal fibronectin …

The hypothalamic-pituitary-adrenocortical (HPA) axis is a major neuroendocrine pathway
that modulates the stress response. The glucocorticoid, cortisol, is the principal end product …

OBJECTIVE: The purpose of this study was to determine whether quantification of
cervicovaginal fluid fetal fibronectin (fFN) improves diagnostic accuracy of spontaneous …

Please cite this paper as: Conde‐Agudelo A, Papageorghiou A, Kennedy S, Villar J. Novel
biomarkers for the prediction of the spontaneous preterm birth phenotype: a systematic …