Inducing mucosal IgA: a challenge for vaccine adjuvants and delivery systems
PN Boyaka - The Journal of Immunology, 2017 - journals.aai.org
Abstract Mucosal IgA or secretory IgA (SIgA) are structurally equipped to resist chemical
degradation in the harsh environment of mucosal surfaces and enzymes of host or microbial …
degradation in the harsh environment of mucosal surfaces and enzymes of host or microbial …
Adjuvants and delivery systems based on polymeric nanoparticles for mucosal vaccines
Most pathogens enter the body through mucosal surfaces. Therefore, vaccination through
the mucosal route can greatly enhance the mucosal immune response. Vaccination via the …
the mucosal route can greatly enhance the mucosal immune response. Vaccination via the …
When therapeutic IgA antibodies might come of age
D Sterlin, G Gorochov - Pharmacology, 2021 - karger.com
Background: Extensive efforts have been made in optimizing monoclonal immunoglobulin
(Ig) G antibodies for use in clinical practice. Accumulating evidence suggests that IgA or anti …
(Ig) G antibodies for use in clinical practice. Accumulating evidence suggests that IgA or anti …
[HTML][HTML] The mucoadhesive nanoparticle-based delivery system in the development of mucosal vaccines
Mucosal tissue constitutes the largest interface between the body and the external
environment, regulating the entry of pathogens, particles, and molecules. Mucosal …
environment, regulating the entry of pathogens, particles, and molecules. Mucosal …
Mucosal vaccination: Onward and upward
CJY Tsai, JMS Loh, K Fujihashi… - Expert Review of …, 2023 - Taylor & Francis
Introduction The unique mucosal immune system allows the generation of robust protective
immune responses at the front line of pathogen encounters. The needle-free delivery route …
immune responses at the front line of pathogen encounters. The needle-free delivery route …
Promising adjuvants and platforms for influenza vaccine development
Influenza is one of the major threats to public health. Current influenza vaccines cannot
provide effective protection against drifted or shifted influenza strains. Researchers have …
provide effective protection against drifted or shifted influenza strains. Researchers have …
Nanovaccines to combat drug resistance: the next-generation immunisation
K Manju, SN Raj, HK Ranjini, SC Nayaka… - Future Journal of …, 2023 - Springer
Background The present review envisages the role of nanovaccines to combat the global
challenges of antimicrobial resistance. Nanovaccines are a novel formulation comprised of …
challenges of antimicrobial resistance. Nanovaccines are a novel formulation comprised of …
Mucosal and systemic immune responses to influenza H7N9 antigen HA1–2 co-delivered intranasally with flagellin or polyethyleneimine in mice and chickens
L Song, D Xiong, H Song, L Wu, M Zhang… - Frontiers in …, 2017 - frontiersin.org
Consecutive cases of human infection with H7N9 influenza viruses since 2013 in China
have prompted efforts to develop an effective treatment. Subunit vaccines introduced by …
have prompted efforts to develop an effective treatment. Subunit vaccines introduced by …
Evaluation of the protective efficacy of Poly I: C as an adjuvant for H9N2 subtype Avian influenza inactivated vaccine and its mechanism of action in ducks
A Zhang, H Lai, J Xu, W Huang, Y Liu, D Zhao… - PLoS One, 2017 - journals.plos.org
Current commercial H9 avian influenza vaccines cannot provide satisfactory protective
immunity against antigenic variant influenza viruses in ducks. Poly I: C, when used as an …
immunity against antigenic variant influenza viruses in ducks. Poly I: C, when used as an …
Eye infection with SARS-CoV-2 as a route to systemic immunization?
N Schrage, J Blomet, F Holzer, A Tromme, F Ectors… - Viruses, 2022 - mdpi.com
Infectious diseases of the conjunctiva and cornea usually leave behind both broad local and
systemic immunity. Case reports of SARS-CoV-2-positive conjunctivitis with subsequent …
systemic immunity. Case reports of SARS-CoV-2-positive conjunctivitis with subsequent …