Over recent years, analyses of secretomes (complete sets of secreted proteins) have been
reported in various organisms, cell types, and pathologies and such studies are quickly …

Background Metarhizium anisopliae is an entomopathogenic fungus used in the biological
control of some agricultural insect pests, and efforts are underway to use this fungus in the …

Many pathogenic bacteria translocate virulence factors into their eukaryotic hosts by means
of type IV secretion systems (T4SS) spanning the inner and outer membranes. Genes …

Background: Solubility of recombinant therapeutic enzymes is one of the major purpose their
production in bacterial host The factors such as metabolic system, a cellular stress response …

CytR is a transcription regulator from the LacI family, present in some gamma-proteobacteria
including Escherichia coli and known not only for its cellular role, control of transport and …

Rifampicin (RIF) is one of the most important first-line anti-tuberculosis (TB) drugs, and more
than 90% of RIF-resistant (RR) Mycobacterium tuberculosis clinical isolates belong to …

Background Gene fusion has epigenetic modification functions. The novel proteins encoded
by gene fusion products play a role in cancer development. Therefore, a better …

Background Since membrane protein structures are challenging to crystallize, computational
approaches are essential for elucidating the sequence-to-structure relationships. Structural …

Chromosome 4 is the fourth largest chromosome, containing approximately 191 megabases
(∼ 6.4% of the human genome) with 757 protein-coding genes. A number of marker genes …

Secreted proteins play important roles in several biological processes such as growth,
proliferation differentiation, cell-cell communication, migration, and apoptosis; moreover …