The role of exosomal PD-L1 in tumor progression and immunotherapy
F Xie, M Xu, J Lu, L Mao, S Wang - Molecular cancer, 2019 - Springer
Programmed death ligand 1 (PD-L1), a type I transmembrane protein, binds to its receptor
PD-1 to suppress the activation of T cells, thereby maintaining immunological homeostasis …
PD-1 to suppress the activation of T cells, thereby maintaining immunological homeostasis …
Exosomes: potential disease biomarkers and new therapeutic targets
Exosomes are extracellular vesicles released by cells, both constitutively and after cell
activation, and are present in different types of biological fluid. Exosomes are involved in the …
activation, and are present in different types of biological fluid. Exosomes are involved in the …
Hypercoagulability of COVID‐19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis
M Panigada, N Bottino, P Tagliabue… - … of thrombosis and …, 2020 - Wiley Online Library
Background The severe inflammatory state secondary to COVID‐19 leads to a severe
derangement of hemostasis that has been recently described as a state of disseminated …
derangement of hemostasis that has been recently described as a state of disseminated …
Higher yield and enhanced therapeutic effects of exosomes derived from MSCs in hydrogel-assisted 3D culture system for bone regeneration
W Yu, S Li, X Guan, N Zhang, X Xie, K Zhang… - Biomaterials Advances, 2022 - Elsevier
Exosomes are emerging in tissue engineering as up-and-coming acellular therapeutics,
circumventing common restrictions inherent to cell-based therapies. The characteristics and …
circumventing common restrictions inherent to cell-based therapies. The characteristics and …
Sepsis plasma-derived exosomal miR-1-3p induces endothelial cell dysfunction by targeting SERP1
M Gao, T Yu, D Liu, Y Shi, P Yang, J Zhang… - Clinical …, 2021 - portlandpress.com
Acute lung injury (ALI) is the leading cause of death in sepsis patients. Exosomes participate
in the occurrence and development of ALI by regulating endothelial cell inflammatory …
in the occurrence and development of ALI by regulating endothelial cell inflammatory …
Coagulopathy and thromboembolic events in patients with SARS-CoV-2 infection: pathogenesis and management strategies
In October 2019, a viral infectious disease appeared in the city of Wuhan in China. A new
betacoronavirus, SARS-CoV-2, has been recognized as the responsible pathogen in this …
betacoronavirus, SARS-CoV-2, has been recognized as the responsible pathogen in this …
Role of extracellular vesicles in cell death and inflammation
R Sanwlani, L Gangoda - Cells, 2021 - mdpi.com
Extracellular vesicles (EVs) have been identified as novel mediators of intercellular
communication. They work via delivering the sequestered cargo to cells in the close vicinity …
communication. They work via delivering the sequestered cargo to cells in the close vicinity …
Outer membrane lipid secretion and the innate immune response to gram-negative bacteria
The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that
consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The …
consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The …
Lactobacillus plantarum-derived extracellular vesicles induce anti-inflammatory M2 macrophage polarization in vitro
Probiotics offer various health benefits. Lactobacillus plantarum has been used for decades
to enhance human intestinal mucosal immunity and improve skin barrier integrity …
to enhance human intestinal mucosal immunity and improve skin barrier integrity …
Exosomes in sepsis
Sepsis is a severe state of infection with high mortality. Pathogen-associated molecular
patterns and damage-associated molecular patterns (DAMPs) initiate dysregulated systemic …
patterns and damage-associated molecular patterns (DAMPs) initiate dysregulated systemic …