[HTML][HTML] The humanized mouse model: what added value does it offer for HIV research?
L Baroncini, S Bredl, KP Nicole, RF Speck - Pathogens, 2023 - mdpi.com
In the early 2000s, novel humanized mouse models based on the transplantation of human
hematopoietic stem and progenitor cells (HSPCs) into immunocompromised mice were …
hematopoietic stem and progenitor cells (HSPCs) into immunocompromised mice were …
[HTML][HTML] The menstrual cycle regulates migratory CD4 T-cell surveillance in the female reproductive tract via CCR5 signaling
ME Williams, FP Hardnett, AN Sheth, AN Wein… - Mucosal …, 2024 - Elsevier
Despite their importance for immunity against sexually transmitted infections, the
composition of female reproductive tract (FRT) memory T-cell populations in response to …
composition of female reproductive tract (FRT) memory T-cell populations in response to …
[HTML][HTML] Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate
F Bradley, M Franzén Boger, V Kaldhusdal… - PLoS …, 2022 - journals.plos.org
Depot medroxyprogesterone acetate (DMPA) is an injectable hormonal contraceptive used
by millions of women worldwide. However, experimental studies have associated DMPA use …
by millions of women worldwide. However, experimental studies have associated DMPA use …
[HTML][HTML] Comparing Current and Next-Generation Humanized Mouse Models for Advancing HIV and HIV/Mtb Co-Infection Studies
In people living with HIV, Mycobacterium tuberculosis (Mtb) is the major cause of death. Due
to the increased morbidity/mortality in co-infection, further research is urgently required. A …
to the increased morbidity/mortality in co-infection, further research is urgently required. A …
pH-sensitive dual-preventive siRNA-based nanomicrobicide reactivates autophagy and inhibits HIV infection in vaginal CD4+ cells
S Yang, Y Chen, J Gu, A Harris, RC Su… - Journal of Controlled …, 2024 - Elsevier
Women are more susceptible to HIV transmission through unprotected heterosexual
intercourse due to biological and social vulnerabilities. Intravaginal delivery of siRNAs …
intercourse due to biological and social vulnerabilities. Intravaginal delivery of siRNAs …
[HTML][HTML] Female Sex Hormones Upregulate the Replication Activity of HIV-1 Sub-Subtype A6 and CRF02_AG but Not HIV-1 Subtype B
M Nosik, E Berezhnya, E Bystritskaya, I Kiseleva… - Pathogens, 2023 - mdpi.com
More than 50% of all people living with HIV worldwide are women. Globally, HIV/AIDS is the
leading cause of death among women aged 15 to 44. The safe and effective methods of …
leading cause of death among women aged 15 to 44. The safe and effective methods of …
[HTML][HTML] Repeated Intravaginal Inoculation of Zika Virus Protects Cynomolgus Monkeys from Subcutaneous Superchallenge
Zika virus (ZIKV) outbreaks in Central and South America caused severe public health
problems in 2015 and 2016. These outbreaks were finally contained through several …
problems in 2015 and 2016. These outbreaks were finally contained through several …
[HTML][HTML] The progestin medroxyprogesterone acetate affects HIV-1 production in human lymphoid tissue explants in a dose-dependent and glucocorticoid-like fashion
C Vanpouille, G Günaydın, M Jangard, M Clerici… - Viruses, 2021 - mdpi.com
The association between the use of the injectable contraceptive depot
medroxyprogesterone acetate and HIV-1 susceptibility has been addressed mainly in …
medroxyprogesterone acetate and HIV-1 susceptibility has been addressed mainly in …
COMBATING THE HIV/TB CO-INFECTION SYNDEMIC: TESTING A NOVEL RESPIRATORY MUCOSAL ADENOVIRAL TUBERCULOSIS VACCINE IN NAÏVE AND …
A Chacon - 2023 - macsphere.mcmaster.ca
HIV and Tuberculosis (TB) co-infection place an immense burden on health care systems as
they act in synergy to worsen disease prognoses. TB is the most common cause of death in …
they act in synergy to worsen disease prognoses. TB is the most common cause of death in …
Investigating Hiv-1 Transmission To Human Cervix Using Reporter Virus Technologies
DF Indihar - 2024 - digitalcommons.library.uab.edu
Around 39 million people globally are currently infected with Human immunodeficiency virus
1 (HIV-1), more than half of whom are women. HIV-1 is a retrovirus that infects and depletes …
1 (HIV-1), more than half of whom are women. HIV-1 is a retrovirus that infects and depletes …