Interplay of low-density lipoprotein receptors, LRPs, and lipoproteins in pulmonary hypertension
The low-density lipoprotein receptor (LDLR) gene family includes LDLR, very LDLR, and
LDL receptor–related proteins (LRPs) such as LRP1, LRP1b (aka LRP-DIT), LRP2 (aka …
LDL receptor–related proteins (LRPs) such as LRP1, LRP1b (aka LRP-DIT), LRP2 (aka …
LRP1B: a giant lost in cancer translation
C Príncipe, IJ Dionísio de Sousa, H Prazeres… - Pharmaceuticals, 2021 - mdpi.com
Low-density lipoprotein receptor-related protein 1B (LRP1B) is a giant member of the LDLR
protein family, which includes several structurally homologous cell surface receptors with a …
protein family, which includes several structurally homologous cell surface receptors with a …
[HTML][HTML] LRP1B mutations are associated with favorable outcomes to immune checkpoint inhibitors across multiple cancer types
LC Brown, MD Tucker, R Sedhom… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Low-density lipoprotein receptor-related protein 1b (encoded by LRP1B) is a
putative tumor suppressor, and preliminary evidence suggests LRP1B-mutated cancers may …
putative tumor suppressor, and preliminary evidence suggests LRP1B-mutated cancers may …
Decoding the DNA methylome of mantle cell lymphoma in the light of the entire B cell lineage
AC Queiros, R Beekman, R Vilarrasa-Blasi… - Cancer cell, 2016 - cell.com
We analyzed the in silico purified DNA methylation signatures of 82 mantle cell lymphomas
(MCL) in comparison with cell subpopulations spanning the entire B cell lineage. We …
(MCL) in comparison with cell subpopulations spanning the entire B cell lineage. We …
Increased levels of the long intergenic non–protein coding RNA POU3F3 promote DNA methylation in esophageal squamous cell carcinoma cells
Background & Aims Thousands of long intergenic non–protein coding RNAs (lincRNAs)
have been identified in mammals via genome-wide sequencing studies. Many are …
have been identified in mammals via genome-wide sequencing studies. Many are …
Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact
WG Tong, WG Wierda, E Lin, SQ Kuang, BN Bekele… - Epigenetics, 2010 - Taylor & Francis
We performed a genome-wide analysis of aberrant DNA methylation in chronic lymphocytic
leukemia (CLL) using methylated CpG island amplification (MCA) coupled with a promoter …
leukemia (CLL) using methylated CpG island amplification (MCA) coupled with a promoter …
Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing
We developed a novel approach for conducting multisample, multigene, ultradeep bisulfite
sequencing analysis of DNA methylation patterns in clinical samples. A massively parallel …
sequencing analysis of DNA methylation patterns in clinical samples. A massively parallel …
Identification of novel DNA methylation markers in cervical cancer
Testing for DNA methylation has potential in cancer screening. Most previous studies of
DNA methylation in cervical cancer used a candidate gene approach. The aim our study …
DNA methylation in cervical cancer used a candidate gene approach. The aim our study …
Global methylation profiling for risk prediction of prostate cancer
Purpose: The aim of this study was to investigate the promoter hypermethylation as
diagnostic markers to detect malignant prostate cells and as prognostic markers to predict …
diagnostic markers to detect malignant prostate cells and as prognostic markers to predict …
DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma
R Shaknovich, H Geng, NA Johnson… - Blood, The Journal …, 2010 - ashpublications.org
Expression profiling has shown 2 main and clinically distinct subtypes of diffuse large B-cell
lymphomas (DLBCLs): germinal-center B cell–like (GCB) and activated B cell–like (ABC) …
lymphomas (DLBCLs): germinal-center B cell–like (GCB) and activated B cell–like (ABC) …