An overview of the methods used to increase the dissolution rate of meloxicam for oral administration
B Jadach, A Froelich, A Tatarek, T Osmałek - Journal of Drug Delivery …, 2024 - Elsevier
Oral administration of a drug substance has become one of the most important drug delivery
routes. In chronic diseases such as rheumatoid arthritis or osteoarthritis, oral forms of drugs …
routes. In chronic diseases such as rheumatoid arthritis or osteoarthritis, oral forms of drugs …
The role of pH and dose/solubility ratio on cocrystal dissolution, drug supersaturation and precipitation
Cocrystals that are more soluble than the constituent drug, generate supersaturation levels
during dissolution and are predisposed to conversion to the less soluble drug. Drug release …
during dissolution and are predisposed to conversion to the less soluble drug. Drug release …
Pharmaceutical salts of piroxicam and meloxicam with organic counterions
S Huang, DS Venables, SE Lawrence - Crystal growth & design, 2022 - ACS Publications
Piroxicam (PRM) and meloxicam (MEL) are two nonsteroidal anti-inflammatory drugs,
belonging to the Biopharmaceutics Classification System Class II drugs. In this study, six …
belonging to the Biopharmaceutics Classification System Class II drugs. In this study, six …
Eutexia for enhanced dissolution rate and anti-inflammatory activity of nonsteroidal anti-inflammatory agents: Caffeine as a melting point modulator
Fast dissolution of nonsteroidal anti-inflammatory drugs (NSAIDs) is a prerequisite from
patient perspective. However, most NSAIDs are slowly dissolving acidic compounds …
patient perspective. However, most NSAIDs are slowly dissolving acidic compounds …
Dissolution and permeability properties of co-amorphous formulations of hydrochlorothiazide
M Ruponen, H Rusanen, R Laitinen - Journal of Pharmaceutical Sciences, 2020 - Elsevier
A biopharmaceutics classification system class IV drug, hydrochlorothiazide (HCT), was
combined with co-formers of L-and d-arginine (ARG) and sodium lauryl sulphate (SLS) by …
combined with co-formers of L-and d-arginine (ARG) and sodium lauryl sulphate (SLS) by …
Permeability of glibenclamide through a PAMPA membrane: The effect of co-amorphization
M Ruponen, M Visti, R Ojarinta, R Laitinen - European Journal of …, 2018 - Elsevier
Co-amorphous systems are an attractive alternative for amorphous solid polymer
dispersions in the formulation of poorly soluble drugs. Several studies have revealed that co …
dispersions in the formulation of poorly soluble drugs. Several studies have revealed that co …
Development of a fast dissolving sublingual film containing meloxicam nanocrystals for enhanced dissolution and earlier absorption
Q Song, C Shen, B Shen, W Lian, X Liu, B Dai… - Journal of Drug Delivery …, 2018 - Elsevier
The objective of this work was to prepare and evaluate fast dissolving sublingual films
containing meloxicam nanocrystals (MLX-NS-FDSFs). Nanocrystals (NS) were utilized to …
containing meloxicam nanocrystals (MLX-NS-FDSFs). Nanocrystals (NS) were utilized to …
New Drug Delivery Systems for Stable Oral Absorption: Theory, Strategies, and Applications
S Onoue - Biological and Pharmaceutical Bulletin, 2024 - jstage.jst.go.jp
The oral dosage route still remains the most common and preferred route for drug
administration due to convenient handling, high patient compliance, and cost-effectiveness …
administration due to convenient handling, high patient compliance, and cost-effectiveness …
Amorphous solid dispersion of meloxicam enhanced oral absorption in rats with impaired gastric motility
H Suzuki, K Yakushiji, S Matsunaga… - Journal of …, 2018 - Elsevier
Meloxicam (MEL) shows a slow onset of action in severe pain patients on account of
delayed gastric motility. This study aimed to develop an amorphous solid dispersion (ASD) …
delayed gastric motility. This study aimed to develop an amorphous solid dispersion (ASD) …
Multiparticulate systems of meloxicam for colonic administration in cancer or autoimmune diseases
E Navarro-Ruíz, C Álvarez-Álvarez, MÁ Peña… - Pharmaceutics, 2022 - mdpi.com
The aim of this research is the development of new colonic release systems of meloxicam
(MLX) a non-steroidal anti-inflammatory drug (NSAIDs) with pH and time-dependent …
(MLX) a non-steroidal anti-inflammatory drug (NSAIDs) with pH and time-dependent …