Central regulation of stress-evoked peripheral immune responses
Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …
associated with systemic inflammation. Recent studies have reported stress-induced …
Stroke–heart syndrome: recent advances and challenges
After ischemic stroke, there is a significant burden of cardiovascular complications, both in
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …
Pathophysiology and therapeutic approaches for spinal cord injury
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …
functions. Despite extensive research in the last decades, SCI continues to be a global …
The cholinergic anti-inflammatory pathway inhibits inflammation without lymphocyte relay
The magnitude of innate inflammatory immune responses is dependent on interactions
between peripheral neural and immune cells. In particular, a cholinergic anti-inflammatory …
between peripheral neural and immune cells. In particular, a cholinergic anti-inflammatory …
Research advances of biomaterials-based microenvironment-regulation therapies for repair and regeneration of spinal cord injury
Z Li, Q Wang, H Hu, W Zheng, C Gao - Biomedical Materials, 2021 - iopscience.iop.org
Traumatic spinal cord injury (SCI) usually results in restricted behaviour recovery and even
life-changing paralysis, accompanied with numerous complications. Pathologically, the …
life-changing paralysis, accompanied with numerous complications. Pathologically, the …
Immunomodulatory and regenerative effects of the full and fractioned adipose tissue derived stem cells secretome in spinal cord injury
Adipose tissue derived stem cells (ASCs) are recognized to secret a myriad of molecules
(secretome) know to modulate inflammatory response, promote axonal growth as well …
(secretome) know to modulate inflammatory response, promote axonal growth as well …
Combinatorial therapies for spinal cord injury repair
CS Sousa, A Monteiro, AJ Salgado… - Neural Regeneration …, 2025 - journals.lww.com
Spinal cord injuries have profound detrimental effects on individuals, regardless of whether
they are caused by trauma or non-traumatic events. The compromised regeneration of the …
they are caused by trauma or non-traumatic events. The compromised regeneration of the …
[HTML][HTML] Sympathetic Nerves Coordinate Corneal Epithelial Wound Healing by Controlling the Mobilization of Ly6Chi Monocytes From the Spleen to the Injured …
S He, J Liu, Y Xue, T Fu, Z Li - Investigative ophthalmology & …, 2023 - tvst.arvojournals.org
Purpose: This study aims to investigate the potential involvement of spleen-derived
monocytes in the repair process following corneal epithelial abrasion. Methods: A corneal …
monocytes in the repair process following corneal epithelial abrasion. Methods: A corneal …
Levetiracetam treatment leads to functional recovery after thoracic or cervical injuries of the spinal cord
Spinal cord injury (SCI) leads to dramatic impairments of motor, sensory, and autonomic
functions of affected individuals. Following the primary injury, there is an increased release …
functions of affected individuals. Following the primary injury, there is an increased release …
Pre-clinical assessment of roflumilast Therapy in a thoracic model of Spinal cord Injury
The failure of axons to regenerate after a spinal cord injury (SCI) remains one of the greatest
challenges in neuroscience. The initial mechanical trauma is followed by a secondary injury …
challenges in neuroscience. The initial mechanical trauma is followed by a secondary injury …