Breast cancer (BC) is the most common cancer of women all over the world. BRCA1 and
BRCA2 gene mutations comprise the most important genetic susceptibility of BC. Except for …

BRCA1 gene mutations account for about 25-28% of hereditary Breast Cancer as BRCA1 is
included in the category of high penetrance genes. Except for few commonmutations, there …

Background About 3885 women are diagnosed with breast cancer and 1285 die from the
disease each year in Bulgaria. However no genetic testing to identify the mutations in high …

Background: The incidence of breast cancer in India is on the rise and is rapidly becoming
the number one cancer in females, pushing the cervical cancer to the second position. Most …

Breast and ovarian cancers now account for one in three cancers in Indian women and their
incidence is rising. Major differences in the clinical presentation of breast and ovarian …

Abstract Hereditary breast cancer constitutes 5–10% of all breast cancer cases. Inherited
mutations in the BRCA1 and BRCA2 tumor-suppressor genes account for the majority of …

Background Ovarian cancer (OC) is considered a leading cause of death among women
with gynecological malignancies. OC, like breast cancer, shows a familial predisposition to …

Abstract The germline BRCA1 c. 68_69delAG (185delAG) and c. 5266dupC (5382insC)
mutations are associated with hormone receptor-negative breast cancer (BC). Limited …

Мутации в двух основных высокопенетрантных генах рака молочной железы BRCA1 и
BRCA2 ответственны за 20 и более процентов случаев наследственного рака …

Address: 1 Professor, Department of Medical Microbiology, College of Medicine, University
of Al-Qadisiyah, Diwaniyah, Iraq, Email: hammadi. abttan@ qu. edu. iq, 2 Assist Professor …