MXene-based aptasensors: Advances, challenges, and prospects

S Ullah, F Shahzad, B Qiu, X Fang, A Ammar… - Progress in Materials …, 2022 - Elsevier
The combination of 2D MXenes with high affinity aptamers has resulted in the development
of innovative aptasensing approaches for food/water safety and clinical diagnosis. Aptamers …

Recent progress of SELEX methods for screening nucleic acid aptamers

C Zhu, Z Feng, H Qin, L Chen, M Yan, L Li, F Qu - Talanta, 2023 - Elsevier
Nucleic acid aptamers are oligonucleotide sequences screened by an in vitro methodology
called Systematic Evolution of Ligands by Exponential Enrichment (SELEX). Known as …

[HTML][HTML] Application and development of aptamer in cancer: from clinical diagnosis to cancer therapy

J Han, L Gao, J Wang, J Wang - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Traditional anticancer therapies can cause serious side effects in clinical treatment due to
their nonspecific of tumor cells. Aptamers, also termed as' chemical antibodies', are short …

Biosensors made of synthetic functional nucleic acids toward better human health

EM McConnell, I Cozma, D Morrison, Y Li - Analytical Chemistry, 2019 - ACS Publications
The invention of the in vitro selection technique, or SELEX (Systematic Evolution of Ligands
by EXponential enrichment), in the early 1990s, identified single-stranded (ss) nucleic acid …

[HTML][HTML] Advances of aptamers screened by Cell-SELEX in selection procedure, cancer diagnostics and therapeutics

Y Zhong, J Zhao, J Li, X Liao, F Chen - Analytical biochemistry, 2020 - Elsevier
Aptamers are a class of short artificial single-stranded oligo (deoxy) nucleotides that can
bind to different targets, which generated by Systematic Evolution of Ligands by Exponential …

Application of the catalytic activity of gold nanoparticles for development of optical aptasensors

R Yazdian-Robati, N Hedayati, S Dehghani… - Analytical …, 2021 - Elsevier
Biosensor technology is considered to be a great alternative in analytical techniques over
the conventional methods. Among many recently developed techniques and devices …

[HTML][HTML] Polymer nanoparticles and nanomotors modified by DNA/RNA aptamers and antibodies in targeted therapy of cancer

V Subjakova, V Oravczova, T Hianik - Polymers, 2021 - mdpi.com
Polymer nanoparticles and nano/micromotors are novel nanostructures that are of increased
interest especially in the diagnosis and therapy of cancer. These structures are modified by …

Selection of DNA aptamers for tramadol through the systematic evolution of ligands by exponential enrichment method for fabrication of a sensitive fluorescent …

N Hedayati, SM Taghdisi, R Yazdian-Robati… - … Acta Part A: Molecular …, 2021 - Elsevier
Tramadol hydrochloride (TH), as an atypical opioid and a 4-phenyl-piperidine analogue of
codeine, is mainly used for treating moderate to severe pains. Due to its extensive …

Aptamers functionalized biomolecular nano-vehicles for applications in cancer diagnostics & therapeutics

S Das, A Gupta, TV Vaishnavi, S Walia… - Applied …, 2022 - pubs.thesciencein.org
Given its structural versatility and functional programmability, DNA has emerged as an ideal
scaffold for developing nanoscale materials with emerging applications, including the ones …

Development of aptamer screening against proteins and its applications

Z Li-Ping, Y Ge, XM Zhang, QU Feng - Chinese Journal of Analytical …, 2020 - Elsevier
Aptamers are short single stranded DNA or RNA selected through systematic evolution of
ligands by exponential enrichment (SELEX), which can bind to target molecules with high …