Lipid excipients are applied for numerous purposes such as taste masking, controlled
release, improvement of swallowability and moisture protection. Several melting techniques …

Fluidized bed melt granulation has recently been recognized as a promising technique with
numerous advantages over conventional granulation techniques. The aim of this study was …

Hot-melt coating is a novel and cost-effective solvent-free coating technique. Commonly
used excipients for hot-melt coating are lipid substances. In this work, modified fluidized-bed …

The aim of this work is to follow the agglomeration mechanism of an in situ Fluid Bed Melt
Granulation (FBMG) by means of machine learning with Artificial Neural Network (ANN) …

The in-line control of pharmaceutical processes has become a necessary tool for the
evaluation and follow-up of pharmaceutical dosage forms. In this study, a novel approach to …

The understanding of granule growth mechanisms and the effects of formulation and
operating conditions over product quality and process performance in fluidized bed co-melt …

Konvencionalne metode granulacije pokazuju brojne nedostatke što je razlog za sve veće
interesovanje i ulaganje u razvoj alternativnih metoda. Granulacija topljenjem predstavlja …

Melt granulation in fluid bed processors is an emerging technique, but literature data
regarding the modeling of this granulation method are lacking. In the present study different …

This study describes a novel approach for the use of thermal analysis to study the aftermath
of the fluid bed melt granulation process and to depict the growth mechanism of the granules …

For the past decades, the vast majority of pharmaceutical drug products have been
manufactured by batch processing, a method where all starting materials are charged into …