Multifunctional rolling circle transcription-based nanomaterials for advanced drug delivery
X Ma, Y Zhang, K Huang, L Zhu, W Xu - Biomaterials, 2023 - Elsevier
As the up-and-comer in the development of RNA nanotechnology, RNA nanomaterials
based on functionalized rolling circle transcription (RCT) have become promising carriers for …
based on functionalized rolling circle transcription (RCT) have become promising carriers for …
Biomimetic Mineralized CRISPR/Cas RNA Nanoparticles for Efficient Tumor-Specific Multiplex Gene Editing
Y Liang, J Zhang, C Xu, J Wang, W Han, J Yang… - ACS …, 2023 - ACS Publications
CRISPR/Cas9 systems have great potential to achieve sophisticated gene therapy and cell
engineering by editing multiple genomic loci. However, to achieve efficient multiplex gene …
engineering by editing multiple genomic loci. However, to achieve efficient multiplex gene …
Nanoengineered Polymeric RNA Nanoparticles for Controlled Biodistribution and Efficient Targeted Cancer Therapy
RNA nanotechnology, including rolling circle transcription (RCT), has gained increasing
interest as a fascinating siRNA delivery nanoplatform for biostable and tumor-targetable …
interest as a fascinating siRNA delivery nanoplatform for biostable and tumor-targetable …
Targeting ERCC2 with siRNA Self-Assembled Nanoparticles to Enhance the Cisplatin Response in Bladder Cancer
J Wang, Y Yang, X Zhang, Z Li, Y Chen… - ACS Applied Nano …, 2024 - ACS Publications
Cisplatin resistance in bladder cancer significantly hinders further improvement in clinical
efficacy. This resistance can be mediated through nucleic acid repair pathways to counteract …
efficacy. This resistance can be mediated through nucleic acid repair pathways to counteract …
Rolling circle transcription: A new system to produce RNA microspheres for improving RNAi efficiency in an agriculturally important lepidopteran pest (Mythimna …
Y Zhu, L Kong, X Wang, J Xu, X Qian, Y Yang… - Pesticide Biochemistry …, 2023 - Elsevier
We applied a new RNA interference (RNAi) system using rolling circle transcription (RCT)
technology to generate RNA microspheres (RMS) for targeting two key chitin synthetic …
technology to generate RNA microspheres (RMS) for targeting two key chitin synthetic …
基于滚环转录技术的siRNA 递送策略对粘虫的干扰效果.
朱语彤， 孔令浩， 徐嘉政， 郑旭霞… - Chinese Journal of …, 2024 - search.ebscohost.com
摘要[目的] 评估基于滚环转录技术的siRNA 递送策略对粘虫Mythimna separata 的RNA
干扰效果.[方法] 采用荧光定量PCR, 测定靶标基因Msα-tubulin 和Msβ-tubulin 的沉默效率; …
干扰效果.[方法] 采用荧光定量PCR, 测定靶标基因Msα-tubulin 和Msβ-tubulin 的沉默效率; …