Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals
TA van Beek, P Montoro - Journal of chromatography A, 2009 - Elsevier
The chemical analysis and quality control of Ginkgo leaves, extracts, phytopharmaceuticals
and some herbal supplements is comprehensively reviewed. The review is an update of a …
and some herbal supplements is comprehensively reviewed. The review is an update of a …
Chemistry and Biology of Terpene Trilactones from Ginkgo Biloba
K Strømgaard, K Nakanishi - … Chemie International Edition, 2004 - Wiley Online Library
Ginkgo biloba, the ginkgo tree, is the oldest living tree, with a long history of use in traditional
Chinese medicine. In recent years, the leaf extracts have been widely sold as phytomedicine …
Chinese medicine. In recent years, the leaf extracts have been widely sold as phytomedicine …
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia
MB Pappalardi, K Keenan, M Cockerill, WA Kellner… - Nature cancer, 2021 - nature.com
DNA methylation, a key epigenetic driver of transcriptional silencing, is universally
dysregulated in cancer. Reversal of DNA methylation by hypomethylating agents, such as …
dysregulated in cancer. Reversal of DNA methylation by hypomethylating agents, such as …
Convergence and divergence of bitterness biosynthesis and regulation in Cucurbitaceae
Y Zhou, Y Ma, J Zeng, L Duan, X Xue, H Wang, T Lin… - Nature plants, 2016 - nature.com
Differentiation of secondary metabolite profiles in closely related plant species provides
clues for unravelling biosynthetic pathways and regulatory circuits, an area that is still …
clues for unravelling biosynthetic pathways and regulatory circuits, an area that is still …
Terpene trilactones from Gingko biloba: from ancient times to the 21st century
K Nakanishi - Bioorganic & medicinal chemistry, 2005 - Elsevier
Ginkgolides were always close to my heart. I continue to be strongly attracted to Ginkgo
biloba, the ginkgolides and bilobalide. Starting in 1963, I became fascinated by these …
biloba, the ginkgolides and bilobalide. Starting in 1963, I became fascinated by these …
Development and application of diazirines in biological and synthetic macromolecular systems
A Blencowe, W Hayes - Soft Matter, 2005 - pubs.rsc.org
Many different reagents and methodologies have been utilised for the modification of
synthetic and biological macromolecular systems. In addition, an area of intense research at …
synthetic and biological macromolecular systems. In addition, an area of intense research at …
Photoactivatable lipid probes for studying biomembranes by photoaffinity labeling
Y Xia, L Peng - Chemical reviews, 2013 - ACS Publications
1.1. Biomembranes Biological membranes consist mainly of lipids and proteins (Figure 1)
and form the boundaries of all cells. The major lipids present in biomembranes are …
and form the boundaries of all cells. The major lipids present in biomembranes are …
Decarboxylative amination: diazirines as single and double electrophilic nitrogen transfer reagents
PP Chandrachud, L Wojtas… - Journal of the American …, 2020 - ACS Publications
The ubiquity of nitrogen-containing small molecules in medicine necessitates the continued
search for improved methods for C–N bond formation. Electrophilic amination often requires …
search for improved methods for C–N bond formation. Electrophilic amination often requires …
Azido push− pull fluorogens photoactivate to produce bright fluorescent labels
Dark azido push− pull chromophores have the ability to be photoactivated to produce bright
fluorescent labels suitable for single-molecule imaging. Upon illumination, the aryl azide …
fluorescent labels suitable for single-molecule imaging. Upon illumination, the aryl azide …
Development of potential antitumor agents from the scaffolds of plant-derived terpenoid lactones
Y Ren, AD Kinghorn - Journal of medicinal chemistry, 2020 - ACS Publications
Naturally occurring terpenoid lactones and their synthetic derivatives have attracted
increasing interest for their promising antitumor activity and potential utilization in the …
increasing interest for their promising antitumor activity and potential utilization in the …