What can we teach Lymnaea and what can Lymnaea teach us?

V Rivi, C Benatti, K Lukowiak, C Colliva… - Biological …, 2021 - Wiley Online Library
This review describes the advantages of adopting a molluscan complementary model, the
freshwater snail Lymnaea stagnalis, to study the neural basis of learning and memory in …

The unlimited potential of the great pond snail, Lymnaea stagnalis

I Fodor, AAA Hussein, PR Benjamin, JM Koene… - Elife, 2020 - elifesciences.org
Only a limited number of animal species lend themselves to becoming model organisms in
multiple biological disciplines: one of these is the great pond snail, Lymnaea stagnalis …

The role of non-coding RNAs in the formation of long-term associative memory after single-trial learning in Lymnaea

G Kemenes, PR Benjamin, I Kemenes - Frontiers in Behavioral …, 2022 - frontiersin.org
Investigations of the molecular mechanisms of long-term associative memory have revealed
key roles for a number of highly evolutionarily conserved molecular pathways in a variety of …

A circuit mechanism linking past and future learning through shifts in perception

M Crossley, PR Benjamin, G Kemenes, K Staras… - Science …, 2023 - science.org
Long-term memory formation is energetically costly. Neural mechanisms that guide an
animal to identify fruitful associations therefore have important survival benefits. Here, we …

A central control circuit for encoding perceived food value

M Crossley, K Staras, G Kemenes - Science Advances, 2018 - science.org
Hunger state can substantially alter the perceived value of a stimulus, even to the extent that
the same sensory cue can trigger antagonistic behaviors. How the nervous system uses …

Proactive and retroactive interference with associative memory consolidation in the snail Lymnaea is time and circuit dependent

M Crossley, FD Lorenzetti, S Naskar, M O'Shea… - Communications …, 2019 - nature.com
Interference-based forgetting occurs when new information acquired either before or after a
learning event attenuates memory expression (proactive and retroactive interference …

A flavonoid, quercetin, is capable of enhancing long-term memory formation if encountered at different times in the learning, memory formation, and memory recall …

V Rivi, A Batabyal, C Benatti, JMC Blom… - Journal of Comparative …, 2021 - Springer
A major extrinsic factor influencing memory and neuro-cognitive performances across taxa is
diet. Studies from vertebrates have shown the effects of a flavonoid rich diet on cognitive …

Lateralization of short-and long-term visual memories in an insect

AS David Fernandes, JE Niven - Proceedings of the …, 2020 - royalsocietypublishing.org
The formation of memories within the vertebrate brain is lateralized between hemispheres
across multiple modalities. However, in invertebrates evidence for lateralization is restricted …

Reversal of Age-Related Learning Deficiency by the Vertebrate PACAP and IGF-1 in a Novel Invertebrate Model of Aging: The Pond Snail (Lymnaea stagnalis)

Z Pirger, S Naskar, Z László, G Kemenes… - … Series A: Biomedical …, 2014 - academic.oup.com
With the increase of life span, nonpathological age-related memory decline is affecting an
increasing number of people. However, there is evidence that age-associated memory …

A two-neuron system for adaptive goal-directed decision-making in Lymnaea

M Crossley, K Staras, G Kemenes - Nature Communications, 2016 - nature.com
During goal-directed decision-making, animals must integrate information from the external
environment and their internal state to maximize resource localization while minimizing …