Mechanisms of action of currently used antiseizure drugs
GJ Sills, MA Rogawski - Neuropharmacology, 2020 - Elsevier
Antiseizure drugs (ASDs) prevent the occurrence of seizures; there is no evidence that they
have disease-modifying properties. In the more than 160 years that orally administered …
have disease-modifying properties. In the more than 160 years that orally administered …
Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol
P Alves, C Amaral, N Teixeira… - Pharmacological …, 2020 - Elsevier
Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …
being regulated in several countries. However, the psychotropic effects of Δ 9 …
Recent advances in Cannabis sativa genomics research
Cannabis (Cannabis sativa L.) is one of the oldest cultivated plants purported to have
unique medicinal properties. However, scientific research of cannabis has been restricted by …
unique medicinal properties. However, scientific research of cannabis has been restricted by …
Pharmacoresistance–Epidemiology, mechanisms, and impact on epilepsy treatment
M Janmohamed, MJ Brodie, P Kwan - Neuropharmacology, 2020 - Elsevier
Understanding the natural history of and factors associated with pharmacoresistant epilepsy
provides the foundation for formulating mechanistic hypotheses that can be evaluated to …
provides the foundation for formulating mechanistic hypotheses that can be evaluated to …
Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions
LL Anderson, NL Absalom, SV Abelev, IK Low… - …, 2019 - Wiley Online Library
Objective Cannabidiol (CBD) has been approved by the US Food and Drug Administration
(FDA) to treat intractable childhood epilepsies, such as Dravet syndrome and Lennox …
(FDA) to treat intractable childhood epilepsies, such as Dravet syndrome and Lennox …
The Genomics of Cannabis and Its Close Relatives
I Kovalchuk, M Pellino, P Rigault… - Annual Review of …, 2020 - annualreviews.org
Cannabis sativa L. is an important yet controversial plant with a long history of recreational,
medicinal, industrial, and agricultural use, and together with its sister genus Humulus, it …
medicinal, industrial, and agricultural use, and together with its sister genus Humulus, it …
[HTML][HTML] Effects of chronic cannabidiol treatment in the rat chronic unpredictable mild stress model of depression
Several neuropharmacological actions of cannabidiol (CBD) due to the modulation of the
endocannabinoid system as well as direct serotonergic and gamma-aminobutyric acidergic …
endocannabinoid system as well as direct serotonergic and gamma-aminobutyric acidergic …
[HTML][HTML] The molecular mechanisms that underpin the biological benefits of full-spectrum cannabis extract in the treatment of neuropathic pain and inflammation
ZH Maayah, S Takahara, M Ferdaoussi… - Biochimica Et Biophysica …, 2020 - Elsevier
Cannabis has been shown to be beneficial in the treatment of pain and inflammatory
diseases. The biological effect of cannabis is mainly attributed to two major cannabinoids …
diseases. The biological effect of cannabis is mainly attributed to two major cannabinoids …
A randomized controlled trial of topical cannabidiol for the treatment of thumb basal joint arthritis
JT Heineman, GL Forster, KL Stephens… - The Journal of hand …, 2022 - Elsevier
Purpose Since the passage of the Agricultural Improvement Act of 2018, hand surgeons
have increasingly encountered patients seeking counseling on over-the-counter, topical …
have increasingly encountered patients seeking counseling on over-the-counter, topical …
[HTML][HTML] Cannabidiol and cannabigerol exert antimicrobial activity without compromising skin microbiota
M Luz-Veiga, M Amorim, I Pinto-Ribeiro… - International Journal of …, 2023 - mdpi.com
Cannabidiol (CBD) and cannabigerol (CBG) are two pharmacologically active
phytocannabinoids of Cannabis sativa L. Their antimicrobial activity needs further …
phytocannabinoids of Cannabis sativa L. Their antimicrobial activity needs further …