Linear and nonlinear rheology of living cells

P Kollmannsberger, B Fabry - Annual review of materials …, 2011 - annualreviews.org
Living cells are an active soft material with fascinating mechanical properties. Under
mechanical loading, cells exhibit creep and stress relaxation behavior that follows a power …

Cell mechanics: dissecting the physical responses of cells to force

BD Hoffman, JC Crocker - Annual review of biomedical …, 2009 - annualreviews.org
It is now widely appreciated that normal tissue morphology and function rely upon cells'
ability to sense and generate forces appropriate to their correct tissue context. Although the …

A hierarchical cellular structural model to unravel the universal power-law rheological behavior of living cells

JT Hang, Y Kang, GK Xu, H Gao - Nature communications, 2021 - nature.com
Living cells are a complex soft material with fascinating mechanical properties. A striking
feature is that, regardless of their types or states, cells exhibit a universal power-law …

Universal physical responses to stretch in the living cell

X Trepat, L Deng, SS An, D Navajas, DJ Tschumperlin… - Nature, 2007 - nature.com
With every beat of the heart, inflation of the lung or peristalsis of the gut, cell types of diverse
function are subjected to substantial stretch. Stretch is a potent stimulus for growth …

Nonlinear viscoelasticity of adherent cells is controlled by cytoskeletal tension

P Kollmannsberger, CT Mierke, B Fabry - Soft Matter, 2011 - pubs.rsc.org
The viscoelastic response of living cells to small external forces and deformations is
characterized by a weak power law in time. The elastic modulus of cells and the power law …

Rheology of rounded mammalian cells over continuous high-frequencies

G Fläschner, CI Roman, N Strohmeyer… - Nature …, 2021 - nature.com
Understanding the viscoelastic properties of living cells and their relation to cell state and
morphology remains challenging. Low-frequency mechanical perturbations have …

Universality in cell mechanics

X Trepat, G Lenormand, JJ Fredberg - Soft Matter, 2008 - pubs.rsc.org
The cytoskeleton (CSK) of the adherent living cell is arguably the most complex form of soft
matter that exists in nature. It is constituted by hundreds of different proteins that interact with …

Rheological properties of the eukaryotic cell cytoskeleton

PA Pullarkat, PA Fernández, A Ott - Physics Reports, 2007 - Elsevier
The mechanical properties of cells are dominated by the cytoskeleton, a crosslinked network
of protein filaments. Unlike synthetic polymer networks, the cell cytoskeleton is a highly …

Glass transition and rheological redundancy in F-actin solutions

C Semmrich, T Storz, J Glaser… - Proceedings of the …, 2007 - National Acad Sciences
The unique mechanical performance of animal cells and tissues is attributed mostly to their
internal biopolymer meshworks. Its perplexing universality and robustness against structural …

Rheological behavior of living cells is timescale-dependent

D Stamenović, N Rosenblatt, M Montoya-Zavala… - Biophysical journal, 2007 - cell.com
The dynamic mechanical behavior of living cells has been proposed to result from timescale-
invariant processes governed by the soft glass rheology theory derived from soft matter …