Alternative splicing of mRNA precursors is a nearly ubiquitous and extremely flexible point of
gene control in humans. It provides cells with the opportunity to create protein isoforms of …

Hu proteins are RNA-binding proteins involved in diverse biological processes. The
neuronal members of the Hu family, HuB, HuC, and HuD play important roles in neuronal …

RNA-binding proteins (RBPs) and microRNAs (miRNAs) are potent post-transcriptional
regulators of gene expression. Here, we show that the RBP HuR reduced c-Myc expression …

The human embryonic lethal abnormal vision-like protein, HuR, is a member of the Hu family
of RNA-binding proteins. Over the past decade, this ubiquitously expressed protein has …

Cancer‐related gene expression programs are strongly influenced by posttranscriptional
mechanisms. The RNA‐binding protein HuR is highly abundant in many cancers. Numerous …

The RNA binding protein HuR regulates the stability of many target mRNAs. Here, we report
that HuR associated with the 3′ untranslated region of the mRNA encoding the longevity …

The levels of hypoxia-inducible factor 1α (HIF-1α) are tightly controlled. Here, we
investigated the posttranscriptional regulation of HIF-1α expression in human cervical …

During the last decade evidence from numerous studies has been accumulated
demonstrating that posttranscriptional gene regulation including mRNA turnover and …

Careful regulation of mRNA half-lives is a fundamental mechanism allowing cells to quickly
respond to changing environmental conditions. The mRNA-binding Hu proteins are …

The RNA-binding protein HuR can stabilize and/or regulate the translation of target mRNAs,
thereby affecting the cellular responses to immune, proliferative, and damaging agents …