The synthetic strategies involving the construction and cleavage of a bond represent the
central theme in organic synthesis. The cleavage of a bond is achieved either by weakening …

The fusion of pyrazole scaffold with other skeletons creates a class of attractive molecules,
demonstrating significant biological and chemical potentiality in the development of …

Condensed pyrazole derivatives are important heterocyclic compounds due to their
excellent biological activities and have been widely applied in pharmaceutical and …

The antiaromatic ring of norcorrole, a contracted tetrapyrrolic porphyrinoid, was subjected to
[2+ 3] dipolar cycloaddition of iminonitriles. The paratropic character of the resulting chiral …

Pregnenolone (1) was used as a template to develop new anticancer compounds. Ring D
modification of 1 through its reaction with cyanoacetylhydrazine (2) gave the hydrazide …

Acetylisoxazolines were synthesized by the reaction of natural (R)-limonene and (R)-
carvone with acetone in the presence of iron (III) nitrate. The reaction showed to be highly …

Pyrazole, a privileged class of heterocyclic compounds, constitute an interesting template for
medicinal chemistry and is represented by several commercial drugs like Sildenafil …

Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones
- Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C3OB41815D Royal …

Abstract The $[2+ 2] $-, $[4+ 2] $-and $[3+ 2] $-cycloaddition reactions of hydrazones and 1,
2-diazabuta-1, 3-dienes, azomethine imines, nitrile imines and azomethine ylides formed …

This review aims to describe the different strategies developed so far for the synthesis of furo
[2, 3-c] pyrazole, furo [3, 2-c] pyrazole, dihydrofuro [2, 3-c] pyrazole, dihydrofuro [3, 4-c] …