Cell–cell junctions in focus–imaging junctional architectures and dynamics at high resolution

V Janssen, S Huveneers - Journal of Cell Science, 2024 - journals.biologists.com
Studies utilizing electron microscopy and live fluorescence microscopy have significantly
enhanced our understanding of the molecular mechanisms that regulate junctional …

[PDF][PDF] Cardiac mechano-electric crosstalk: multi-scale observations, computational integration, and clinical implications

R Emig, EA MacDonald, TA Quinn - The Journal of Physiology, 2024 - quinnlaboratory.com
Almost all aspects of cardiac electrical function are mechano-sensitive. From excitation of
the sinoatrial node (MacDonald & Quinn, 2021), to conduction through the Purkinje network …

Early atrial remodelling drives arrhythmia in Fabry Disease

A Roy, C O'Shea, A Dasi, L Patel, M Cumberland… - bioRxiv, 2024 - biorxiv.org
Background: Fabry disease (FD) is an X-linked lysosomal storage disorder caused by α-
galactosidase A (α-Gal A) deficiency, resulting in multi-organ accumulation of sphingolipid …