[HTML][HTML] Current analytical methods to monitor type 2 diabetes medication in biological samples

S Rakusanova, T Cajka - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
We review the current analytical methods for analyzing type 2 diabetes (T2D) medication in
human and animal samples. We discuss the advantages and limitations during sample …

Ultrasound-assisted dispersive liquid–liquid microextraction for determination of three gliflozins in human plasma by HPLC/DAD

MM Mabrouk, SM Soliman, HM El-Agizy… - … of Chromatography B, 2020 - Elsevier
A novel, highly sensitive ultrasound-assisted dispersive liquid–liquid microextraction (UA-
DLLME) high performance liquid chromatography with diode-array detection (HPLC/DAD) …

Integrating micellar HPLC and green analytical chemistry tools in greenness assessment of five commonly Co-formulated antidiabetic drugs

AE Ibrahim, K Maged, M Elhenawee… - … Chemistry and Pharmacy, 2023 - Elsevier
The ecological impact of routine quality control activities in the pharmaceutical industry is
crucial, producing large amounts of dangerous organic waste. For that, the use of mixed …

A novel microextraction technique aided by air agitation using a natural hydrophobic deep eutectic solvent for the extraction of fluvastatin and empagliflozin from …

K Alhazzani, AZ Alanazi, AM Mostafa, J Barker… - RSC …, 2023 - pubs.rsc.org
This study focuses on the interaction between the antihyperlipidemic drug fluvastatin (FLV)
and the antidiabetic drug empagliflozin (EMP), which are commonly co-administered …

Determination of antihistaminic pharmaceuticals in surface water samples by SPE-LC-MS/MS method

I Kiszkiel-Taudul - Microchemical Journal, 2021 - Elsevier
A liquid chromatography connected with tandem mass spectrometry (LC–MS/MS) method
for simultaneous determination of histamine H 2 receptor antagonists: cimetidine (CMT) …

Greenness assessment of chromatographic methods used for analysis of empagliflozin: a comparative study

EY Santali, IA Naguib, AM Alshehri, YA Alzahrani… - Separations, 2022 - mdpi.com
The analytical chemistry community is attempting to incorporate green chemistry concepts in
the development of analytical techniques to redefine analytical methods and dramatically …

[HTML][HTML] The “depict” strategy for discovering new compounds in complex matrices: Lycibarbarspermidines as a case

C Han, Z Zhang, Z Feng, C Zhai, X Li, Y Shi, X Li… - Journal of …, 2024 - Elsevier
The comprehensive detection and identification of active ingredients in complex matrices is
a crucial challenge. Liquid chromatography coupled with high-resolution mass spectrometry …

Determination of pesticides and their degradation products in water samples by solid-phase extraction coupled with liquid chromatography-mass spectrometry

X Wang, R Jia, Y Song, M Wang, Q Zhao, S Sun - Microchemical Journal, 2019 - Elsevier
In this study, solid-phase extraction (SPE) of the pesticides, including ametryn, prometon,
bentazon, carbendazim, tebuconazole, dimethoate and their degradation products …

Challenges in simultaneous extraction and chromatographic separation of metformin and three SGLT-2 inhibitors in human plasma using LC–MS/MS

PA Shah, PS Shrivastav, V Sharma… - Journal of Pharmaceutical …, 2019 - Elsevier
Optimization of extraction and chromatographic conditions is essential for the simultaneous
analysis of drugs having different physico-chemical properties, especially for in vivo …

Green Analytical Methods based on Chemometrics and UV spectroscopy for the simultaneous estimation of Empagliflozin and Linagliptin

C Mathew, S Varma - Asian Journal of Pharmaceutical Analysis, 2022 - indianjournals.com
Empagliflozin and Linagliptin are used together as a fixed dose combination for type II
diabetes. It is available as fixed-dose combination tablets in 10: 5 and 25: 5 (amount in …