Diffuse large B-cell lymphomas, not otherwise specified, and emerging entities

JY Song, S Dirnhofer, MA Piris, L Quintanilla-Martínez… - Virchows Archiv, 2023 - Springer
Diffuse large B-cell lymphoma (DLBCL) is an aggressive and heterogenous group of
diseases and the most common subtype of non-Hodgkin lymphoma. In the past decade …

Emerging entities: high-grade/large B-cell lymphoma with 11q aberration, large B-cell lymphoma with IRF4 rearrangement, and new molecular subgroups in large B …

L Quintanilla-Martinez, C Laurent, L Soma, SB Ng… - Virchows Archiv, 2023 - Springer
Emerging entities and molecular subgroups in large B-cell lymphomas (LBCLs) were
discussed during the 2022 European Association for Haematopathology/Society for …

Molecular Determinants of Sensitivity to Polatuzumab Vedotin in Diffuse Large B-Cell Lymphoma

SR Corcoran, JD Phelan, J Choi, G Shevchenko… - Cancer …, 2024 - aacrjournals.org
Polatuzumab vedotin (Pola-V) is an antibody–drug conjugate directed to the CD79B subunit
of the B-cell receptor (BCR). When combined with conventional immunochemotherapy, Pola …

[HTML][HTML] Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients …

E Quinten, JH Sepúlveda-Yáñez, MT Koning… - …, 2023 - pmc.ncbi.nlm.nih.gov
Clonal expansion of CD5-expressing B cells, commonly designated as monoclonal B
lymphocytosis (MBL), is a precursor condition for chronic lymphocytic leukemia (CLL). The …

Real-world routine diagnostic molecular analysis for TP53 mutational status is recommended over p53 immunohistochemistry in B-cell lymphomas

LM de Haan, RAL de Groen, FA de Groot… - Virchows Archiv, 2023 - Springer
Previous studies in patients with mature B-cell lymphomas (MBCL) have shown that
pathogenic TP53 aberrations are associated with inferior chemotherapeutic efficacy and …

Sinonasal DLBCL: molecular profiling identifies subtypes with distinctive prognosis and targetable genetic features

PRG Eriksen, F de Groot, E Clasen-Linde… - Blood …, 2024 - ashpublications.org
Primary sinonasal diffuse large B-cell lymphoma (PSDLBCL) is a rare lymphoma with a
variable prognosis and a unique relapse/dissemination pattern involving the central nervous …

Cell-of-origin classification using the Hans and Lymph2Cx algorithms in primary cutaneous large B-cell lymphomas

AMR Schrader, RAL de Groen, R Willemze, PM Jansen… - Virchows Archiv, 2022 - Springer
Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT) and primary
cutaneous follicle center lymphoma with a diffuse population of large cells (PCFCL-LC) are …

Primary bone diffuse large B‐cell lymphoma (PB‐DLBCL): a distinct extranodal lymphoma of germinal centre origin, with a common EZB‐like mutational profile and …

VS Ivanova, J Davies, T Menter, D Wild… - …, 2024 - Wiley Online Library
Aims Primary bone diffuse large B‐cell lymphoma (PB‐DLBCL) is not recognized as a
separate entity by the current classification systems. Here we define and highlight its …

Primary bone lymphoma: a review of the literature with emphasis on histopathology and histogenesis

T Kanavos, E Birbas, A Papoudou-Bai, E Hatzimichael… - Diseases, 2023 - mdpi.com
Primary bone lymphoma (PBL) is a rare neoplasm of malignant lymphoid cells presenting
with one or more bone lesions without nodal or other extranodal involvement. It accounts for …

Differences in mutational signature of diffuse large B‐cell lymphomas according to the primary organ

HH Koh, SE Yoon, SJ Kim, WS Kim, J Cho - Cancer Medicine, 2023 - Wiley Online Library
Background Comprehensive molecular subtyping of diffuse large B‐cell lymphoma (DLBCL)
through genetic profiling has broadened our understanding of DLBCL biology. In this study …